Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06937 Gsk-1059615 GSE70138 CD34 Human 24h 3.33uM EID0073
Types Number Response transcription factors
Up-regulation 123 SATB1; EGR1; BAZ2B; GABPB1; TSC22D3; HIPK1; FOXO4; NFKBIB; EGR3; ARID4A; CHD3; HDAC4; HDAC6; BRD8; PLAGL1; KAT8; UBE2B; MAML1; CIC; MNT; PHF20; PHF1; FOSB; ZMYM2; BRD3; CBX5; RCOR1; PNRC1; ZFHX4; KAT6A; CREBL2; ALX1; HBP1; PCGF3; SP3; PHIP; TAF10; TBP; SMARCD3; ZNF467; RUNX3; TSC22D1; CEBPD; PSPC1; NFATC1; VDR; MED23; BCL11B; BASP1; LPIN2; SOX4; PBXIP1; ZBED1; CARHSP1; HMGB3; CBX7; ZNF652; NFX1; HTATIP2; RFX5; E2F3; ERF; RNF10; RARA; TBL1XR1; HMGB2; MTA1; ZNF226; MAZ; SP110; SP100; HIVEP2; IRF7; SAP30; MYCBP; SOX9; CHD9; SATB2; ERG; TCF25; SSX1; TRIM22; MKL2; ZBTB1; FOXJ1; TGIF1; NCOA2; ETV5; FOXO1; RERE; MEOX2; RXRA; NFIB; KLF9; STAT6; AFF1; HLTF; MEIS1; BRD2; RBPJ; BCL3; ZNF83; JARID2; TCF4; SMARCA2; HOXC6; PSIP1; IRF8; TLE4; ZEB2; HIC2; AHR; MXI1; ZBTB18; FOXG1; MAFB; MNDA; HOXA5; KDM5D; HMG20B; DACH1; CREG1; ZNF91
Down-regulation 52 RUVBL1; BIRC2; ZNF274; FOSL1; WDR77; PSMC3; ATF5; RBL1; CLOCK; YAP1; THAP10; NOC2L; BRCA1; TEAD4; FOXM1; ETS1; XRCC6; TRIM24; URI1; TBX3; TRIM29; ACTL6A; RAN; PSMC3IP; ID3; ZNF10; GATA4; TAF7; YEATS4; ADRB2; ANKRD1; MYBL1; SHOX2; NKX3-1; SPDEF; CBFB; MYBL2; PTRF; PITX1; CREB3L2; SUB1; ISL1; HDAC9; SALL1; FOSL2; RBPMS; ESR1; SMAD1; TRIB3; SUV39H1; PEG3; PBX3