Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06847 Ex-527 GSE70138 CD34 Human 24h 10uM EID0073
Types Number Response transcription factors
Up-regulation 94 KLF3; HEY1; TAL1; CDYL; KLF4; EGR3; PMS1; WDHD1; ID1; HOXD11; ID3; ZSCAN31; SOHLH2; TWIST1; HOXD3; GATA3; HOXB6; KLF1; FOXF2; HOXB2; TBX1; SMARCA1; TCF7L2; CENPB; FOXF1; ANKRD1; PBX1; POU3F2; ESRRG; ERF; HEY2; TERF2; ZNF512B; ESR1; ZNF148; SIAH2; PEX14; E2F8; MAFB; HBP1; SHOX2; ZNF467; PITX2; ZIC1; NR2F1; POU2AF1; RBFOX2; IFI16; LIN28A; MXI1; HMGB2; IRF7; HIPK2; DAXX; MEIS1; MYCL; SSX1; WWTR1; ZNF423; IRF9; DLX2; CREB3L1; MECOM; NR1H2; SUB1; HOXD1; HOXB5; PAWR; BASP1; ELF4; IRF4; ETS1; SOX11; TRPS1; TRIP6; SATB2; ZEB1; MYRF; SALL2; TFAP2C; TOX; ZNF91; ZNF264; HOXB7; ZNF589; PSIP1; ERBB4; KLF10; WT1; ZBTB18; DACH1; EMX2; SNAI2; ARNT2
Down-regulation 31 SMARCA5; ETV6; AEBP1; CLOCK; SOX10; CRY1; CITED1; NFAT5; DDIT3; CTNNB1; EYA2; NKX3-1; NFKB1; BAZ1A; DDX5; HMGN3; YWHAB; C1QBP; IKBKAP; CREB3L2; BCL3; TBL1X; ZBTB38; ZEB2; CHD7; LITAF; BMI1; SMAD2; HOXC6; KDM5D; HHEX