Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06831 Iniparib GSE70138 CD34 Human 24h 0.37uM EID0073
Types Number Response transcription factors
Up-regulation 50 SAFB2; RXRA; EGR3; BRD3; HDAC1; PHF1; RUNX3; BASP1; TWIST1; SREBF1; HOXC6; NUP62; AFF1; TRIM28; BNC2; ZBTB18; MAF; TFEC; SFPQ; TXNIP; NCOR2; ASCL1; BCL11B; GATA2; NR1D2; PIR; HMGB3; MNDA; WWTR1; CTBP2; NR1H2; HOXB7; TLE4; ZEB2; SMARCA2; KLF4; ZMYM2; TGIF1; KLF2; MXI1; WT1; TGFB1; FOSL2; HOXA5; KDM5D; PSIP1; ZIC1; BHLHE41; MYB; EMX2
Down-regulation 36 SOX9; RRN3; E2F5; IRF8; MLLT10; ATF7IP; KLF6; ATF3; IRF7; IRF9; ZNF107; HDAC9; ZNF195; INSM1; ZNF274; APEX1; ZNF43; GTF2I; YEATS4; ZNF239; ZFP36L2; TCF7L1; IRF6; TFAP2A; SMAD7; TBX3; ELF5; TOX3; ZNF532; ZNF423; DAXX; ZNF91; LITAF; HHEX; MYBL1; TRIB3