Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06796 Nvp-bgj398 GSE70138 CD34 Human 24h 0.04uM EID0033
Types Number Response transcription factors
Up-regulation 87 RB1; TSC22D3; TCERG1; RNF10; SMARCC1; RFX5; NFIL3; EP400; TLE4; TRIM22; PMS1; PLAGL1; SMAD3; TAF9; HLTF; PSIP1; CSDE1; MED23; DDX17; CBFB; RCOR1; ZNF516; ZBTB11; NRIP1; APEX1; PCBD1; MYCN; BCL6; GATA2; SMARCA2; STAT1; PBX1; RHOA; OSR2; KLF4; MEIS1; BAZ1A; ZNF536; AFF1; ZBTB1; HMGB2; BAZ2B; MEOX2; XBP1; DDX5; ELF1; PAXBP1; HOXC6; NCOR2; HIPK1; FOXN3; FLI1; RNF4; ZNF146; CREG1; IFI16; YBX1; COPS5; BMI1; TBL1X; HMBOX1; PITX1; FOXA1; KLF2; GTF2A2; IRF8; CEBPA; FOXO4; EGR3; HTATIP2; TDP2; FOXO1; NR4A1; NFKB1; MBD2; ZFP36L2; ZNF165; HOXB2; ZMIZ1; ZEB2; HOXB7; MYB; TSC22D2; PEG3; NR2F1; NR2F2; MSX1
Down-regulation 111 SCAND1; ZNF35; HMGA1; PQBP1; PLAGL2; NOC2L; SSX1; SMARCD1; JUP; ZNF771; ETV4; ZBTB17; TAF1; ELF3; SMAD1; BRF2; ZBTB48; RFXANK; PRPF6; TGIF2; ZNF266; ZNF593; ZNF200; TRIM27; PFDN5; ZNF562; TAF1A; ZNF671; PSMC3; ZNF557; PROX1; CREB3; MBD3; HDAC9; CBX6; FOXO3; ZNF14; ZNF136; NCOA3; THAP10; ETV5; GTF2F1; ZNF430; MYCL; ZNF688; JUNB; YAP1; ATF5; SMARCD2; NKX3-1; TFDP2; SATB2; ZNF580; PBX2; ZMYND8; ZNF274; THAP7; NR2F6; SALL1; ID4; DRAP1; BTG1; DLX2; HAND1; ZNF91; VDR; CNOT2; ZNF134; POU2AF1; FOXG1; BANP; MXD4; PRRX2; ZNF394; HIPK2; ZNF544; NAB2; SMAD6; TGFB1I1; ID3; BCL11A; NEUROD1; PIR; CCNE1; ZNF124; RBM39; NANOG; BRD4; HIRA; EHF; MTA1; HIC2; EPAS1; JUN; EYA2; LITAF; ERBB4; SOX9; LOXL2; ARID5B; CALR; ZSCAN18; FOXF1; LEF1; IRF6; NFATC4; TFAP2C; MAFB; MKL2; ATF3; FOXF2