Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06782 Idelalisib GSE70138 CD34 Human 24h 0.37uM EID0033
Types Number Response transcription factors
Up-regulation 41 SMARCD3; MITF; CREB5; HMBOX1; SMARCC2; PURA; TSC22D1; NR2F2; CREB3L2; RYBP; RBPJ; AR; TFEC; MEIS1; TBL1X; BTG1; CTBP2; GATA2; KAT6A; MYC; CITED1; PBX1; CREB3L1; RAD21; PEG3; E2F3; ZKSCAN1; YBX1; WT1; CREG1; ZBTB20; ZNF91; TOB1; PBX3; HTATIP2; TP53; NR1H2; TXNIP; MAF; MAGED1; TRIB3
Down-regulation 27 ID3; MDM2; STAT1; ZNF302; ZNF329; PRRX1; SMAD6; ZNF274; ZIC1; TFDP1; CCNE1; SMAD7; HEY1; TEAD4; POU2AF1; JUP; CEBPG; ST18; NFE2L2; TCF21; POU4F1; DLX2; KLF10; ZFPM2; JUN; ZNF423; TFAP2A