Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06773 Bs-181 GSE70138 CD34 Human 24h 10uM EID0033
Types Number Response transcription factors
Up-regulation 522 SMARCC1; SUV39H1; ZNF16; PKNOX2; ZHX2; AFF4; ZIM2; TRIM24; NFATC3; GATA4; NKRF; PEG3; GLI2; ZBTB44; BPTF; THAP10; FHL2; MYCN; PNRC1; GABPB1; FOXL2; YAF2; KLF7; MECOM; C1QBP; TAF5L; UIMC1; FOXA2; RBPJL; PAX6; E2F4; IRF1; ZBTB39; EGR1; MECP2; NEUROD6; NR2C1; PRDM10; TFDP3; JAK2; ZNF184; TCF21; HOXA4; ZNF324; ADNP; PAXBP1; MYC; NKX2-5; AGO2; NFKB2; YEATS4; GFI1; ZZZ3; ZNF654; MYOD1; ATF7; BRD7; HMGXB4; MXD1; MAFK; REL; PEX14; TBX21; PPRC1; MED31; ZNF222; HMGA2; SSX1; TAF4B; HSF1; ZNF7; KDM5B; MYRF; GBX1; CDC5L; SSX7; BCL11A; ASH1L; RAD21; TTF2; SP1; LMO1; MYNN; LHX6; SUPT3H; IKZF2; YEATS2; FOXF1; ZFHX2; PMS1; CREB3L2; TAF5; MED21; SNAI1; ORC2; RNF111; MED17; NR2E1; TRIM16; NFIL3; AFF2; ZSCAN32; TCEA2; POU4F2; SRF; ZNF239; SMAD5; ZNF770; PDLIM1; COPS5; CSDC2; HIRA; EP400; MLXIP; CITED1; SNAI2; NEUROD2; ZNF507; GRHL2; ZNF778; THRA; CREBZF; ZXDC; MAFG; NR2C2; ZNF816; RARG; SCAI; CREB1; SMARCC2; PRDM2; CBL; SSX3; CD3D; ZMYND11; ELK4; SALL1; ZNF221; ZNF426; ETV6; E2F5; L3MBTL1; ZNF174; TOPORS; ZNF202; CIITA; TBX6; ZNF574; ACTL6B; RFX5; THRB; VGLL1; TEAD3; IKZF5; SMAD4; TFCP2L1; TFDP1; RFX1; ZBTB43; MYF6; CUX1; ZBTB16; MEIS2; ATF6B; ZNF652; ZXDB; ZNF423; ZNF85; CSDE1; ZNF215; HOXD11; NR4A3; ARID3A; PROP1; ZKSCAN3; SKI; PLAGL2; ASCL3; SMARCD3; ESRRG; HNF4A; SIX2; NOCT; LHX2; HIPK2; FOXE1; CBX4; GTF2A1; NPAS2; SSBP3; ZNF140; NPM1; HIPK3; BATF3; NHLH1; EP300; CNOT6; CDX4; GTF2I; HOXA6; ZNF250; LITAF; MEN1; ADNP2; PAX8; MXD3; HIF3A; SP4; PHIP; TCF3; SMAD9; NFYA; TUB; ZBED4; RNF10; MED14; YAP1; E2F8; ZNF180; ZNF665; TBX4; HOXB1; PIAS1; NFIC; RXRG; NR2F1; TGIF2; TFCP2; HINFP; BHLHE41; VENTX; MDM2; NFYB; ZNF200; RFXAP; ZNF552; TGS1; ZNF536; URI1; BRD2; TCF7L2; ZNF175; HLF; SUPT7L; FOXH1; NKX2-1; ZNF614; CHD9; TAF9; NFE2L2; ZNF264; TBR1; MAML1; HESX1; ZFPM2; FUBP1; ZNF696; ZNF473; ZSCAN5A; TAF7; PPP1R13L; ARL2BP; POU3F2; ZNF623; ZNF512B; ZNF107; PAX7; HES2; RBFOX2; EMX1; FOXJ2; ZNF154; KLF15; TAF1D; MLLT10; PRDM14; MAFF; PRDM12; CCNH; JUP; COPS2; HHEX; ZNF510; PRDM1; PAX1; FOXJ1; ZBTB3; ZNF669; RSF1; PAWR; SOX13; KMT5A; LBX1; TFAP2A; BARX1; WWC1; CARF; TAF6L; NR6A1; HOXA5; MZF1; KAT6B; MTDH; PRMT2; WHSC1L1; FOXF2; TBL1XR1; NAB2; RORB; SOX3; LHX3; CNBP; EPAS1; ZNF695; ID4; SOX17; CNOT2; PLAG1; ZNF580; DLX5; HIPK1; ZFP2; ZNF33B; ZSCAN31; TFAP4; HIVEP1; NCOA2; ZNF442; BNC2; ZNF500; CDX1; ZNF354A; FOXK2; FOSL2; RARB; POU6F1; TULP2; DLX2; ARID3B; ST18; TP73; POU2AF1; RAN; CHD2; POU4F1; YBX3; GABPA; CDK7; CITED2; TP63; SATB2; TERF2; CBFA2T3; FEZF2; SOX18; TGIF1; HMBOX1; ZKSCAN8; PEX2; ZNF235; NCOA1; HOXA2; CRTC1; GATA2; NKX3-2; CBX2; MED13; ENY2; GBX2; ZNF165; BRD4; PBX1; RING1; ERBB4; TOX; SOX15; TSHZ2; ZBED2; PRDM9; ERF; ZNF195; ISL1; SMAD6; DAXX; SOX11; BRWD1; TTF1; RBL2; HOXD10; GATA6; TAF1A; IKZF3; ZNF177; KLF4; PRRX1; UBP1; DLX4; SP140; ETS1; ZNF273; BLM; CAMTA1; TLX3; HOXC4; CIR1; ZNF74; CTCF; PHOX2B; MAML3; CBX7; SOX12; NFX1; RORC; ZNF131; SOHLH2; ILF2; TLE2; EHF; HES1; OLIG2; KLF3; PBX3; PITX1; FOXD1; ZNF34; ARID5B; CCNT1; TFDP2; SKIL; ANKRD1; HIC2; TRIP6; NFE2L3; PPARA; EN1; PIR; CDK2; ATN1; ZKSCAN1; CDIP1; SALL2; TSC22D1; ZNF304; ZNF573; INSR; KLF13; NFE2; ATF3; TULP3; SIX6; ZNF331; ZNF22; MNDA; SRY; ZNF148; EMX2; CUX2; BACH2; EYA1; ID3; CBX6; TBX5; SMARCA1; STAT1; TCERG1; TRIM22; MKL2; SUMO1; SMARCA2; BCL6; IRF6; ZIC3; ZNF430; ZBTB1; SPDEF; KLF9; WWTR1; HEY1; STAT4; NR4A1; ZNF682; MYBL1; JUN; CHD7; ZEB1; PAX5; ZNF232; ZNF711; SOX2; CEBPG; ETS2; ZNF12; NFATC4; ZNF43; MTA1; TOB1; ZNF667; ZNF91; MEIS1; TCEA1; FOXG1; HBP1; ZMIZ1; SUB1; TRPS1; CREM; PTRF; TRIM29; SIAH2; NFKB1; TRIB3; IFI16; WT1; NR4A2; KLF5; TAL1; YWHAB; FOSB; ZSCAN18; NFKBIA; TSC22D3; NR2F2
Down-regulation 147 SCAND1; IRF7; MAF; BIRC2; CREBL2; ABL1; ADRB2; MITF; HMG20B; PBRM1; RBPJ; MLX; RUNX1; NEDD8; PMF1; HDAC1; NPAT; ZNF212; AFF1; ZNF211; SMARCD2; MXD4; SNW1; MAGED1; VGLL4; IL16; JUNB; RNF4; TSC22D4; ZMYM2; DRAP1; CHD1; ELK3; ZNF468; RXRA; BANP; TXNIP; TADA3; NONO; TBL1X; PFDN5; WHSC1; HNRNPD; ZNF358; KDM5D; CXXC1; PCBD1; ZNF274; RB1; PHF20; E2F3; SND1; NELFB; FLNA; CENPF; BASP1; MNT; SMAD2; ZMIZ2; HTATIP2; UBE2I; FOXJ3; CTBP1; NRBF2; NFE2L1; MTF2; MEF2A; SMARCE1; ZNF83; HDAC7; DNMT3B; SMAD1; HOXB7; KLF11; SP110; HDAC6; HOXB6; EDF1; ATF5; AEBP1; MLXIPL; CTBP2; RLF; JARID2; NRIP1; PARP1; SFPQ; ENO1; HMGN3; HDAC2; ZNF266; BCL10; BBX; GTF2F1; SPI1; BMI1; BRCA1; RHOA; BATF; ING3; MAZ; MYCBP; USF2; NFYC; ZFP36L2; DNAJC1; PCGF2; AATF; MYCL; FOXN3; CEBPA; ZNF432; VDR; ZNF443; PSPC1; SIX1; YBX1; HSBP1; NR2F6; VEZF1; TGFB1; TAF10; PUF60; USP22; REPIN1; MED24; ZBED1; SREBF1; FOXO4; MAFB; NUP62; EZH2; NFAT5; ZBTB18; PBXIP1; ZBTB38; BRPF1; ARID4B; PA2G4; TRIM28; NKX3-1; EGR2; LEF1; NFIB; NR1H2; MYB; MSX1