Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06759	Osimertinib	GSE70138	CD34	Human	24h	0.12uM	EID0033

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	ZNF302; NFE2; KLF1; TXNIP; PPRC1; MYCN; NONO; PBRM1; HMGA1; ZNF266; HOXA10; LYL1; BBX; POU2F1; RYBP; TCF20; ZNF562; HHEX; BTG1; ZNF587; ZNF83; PREB; KLF2; ZNF611; ARID1A; TRIM16; NKX3-1; MED1; PITX1; PA2G4; POLR2A; ZNF148; ZKSCAN1; HSBP1; SIX1; NLK; ZBTB20; LEF1; RUNX1; ZNF146; CBX3; ZNF544; NFAT5; TFEC; ZNF721; SMAD6; ZNF160; BRD4; SCAND1; ZMYND8; SIAH2; ING3; IRF1; KDM2A; NR1D2; HOXB7; CREB1; MITF; NR2F2; DNAJC1; BMI1; LMCD1; IRF5; FOSB; JARID2; CALR; HLTF; MTA1; ELK3; MYB; TP53; TRIM28; MAGED1; ESR1; MEIS1; MAFB; NFKBIA
Down-regulation	95	ITGB3BP; RNF111; PIAS3; MLLT10; ZNF184; FOXI1; MED14; TWIST1; SAP30; BCOR; MED17; FOSL2; LOXL2; ZBED4; ZHX2; TAF11; ZNF394; EGR4; MAML1; NCOR1; THAP10; DLX5; ZBTB16; MAFF; CREM; ZNF281; NR4A3; HIPK1; ZBTB1; TCEA2; SMAD4; ADNP2; ZNF532; CDK9; EYA1; FOXO1; PRRX1; NPAS2; SOX9; TCF7L1; GLI3; SMAD7; SHOX2; LITAF; ZNF215; SOX11; IRF9; NAB2; HMGN3; SOX3; SALL2; CREB3; IRF4; ID4; DAXX; NFYB; TFAP2C; TFAP2A; POU4F1; TOX; RBM39; ETS1; SMARCD2; BHLHE41; NFE2L2; RUNX3; FOXG1; HOXD1; HIRA; NFYA; TP63; KLF10; EGR3; RBBP8; E2F8; ZNF217; WWC1; REL; TCF21; TRIB3; TFDP1; RBFOX2; ZIC3; KLF6; RAD21; EGR2; HIC2; MKL2; NCOA2; ZEB1; SNAI2; MYBL1; MEIS2; ZNF331; FOXF2