Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06758	Osimertinib	GSE70138	CD34	Human	24h	0.37uM	EID0033

Response Information :

Types	Number	Response transcription factors
Up-regulation	28	AFF1; BTG1; CLOCK; ZNF148; MEOX1; BRD2; ERG; TCF4; ZMYND8; TCF7; KDM5A; UBE2I; HOXA5; SMAD7; KDM5D; SMAD6; HNRNPD; KLF5; GATAD2A; MBD2; SIAH2; FOXF1; WT1; YBX3; NR2F2; NR2F1; FOXG1; TOX3
Down-regulation	56	IRF7; KLF11; CAMTA1; NFE2; ZFHX4; STAT1; EGR2; DBP; EGR4; VDR; ID4; JAK2; CITED2; HHEX; TCF7L2; IRF9; ZNF91; BACH1; HMGB2; TSC22D1; EYA2; PRRX1; IFI16; ST18; IRF1; EGR3; CBX3; ISL1; NR4A1; RUNX3; TXNIP; PEG3; TWIST1; JUNB; NCOA4; SP3; HTATIP2; PDLIM1; ZNF117; SUB1; SNAI2; ZBTB18; KLF6; ZFP36L2; ASCL1; ZEB2; DLX5; RAD21; ZEB1; PBXIP1; MEIS2; SHOX2; BHLHE41; BAZ1A; NR1H2; CDK2