Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06746 Motesanib GSE70138 CD34 Human 24h 1.11uM EID0033
Types Number Response transcription factors
Up-regulation 70 PDLIM1; ERBB2; GATA2; ZNF83; DMTF1; ATF2; CEBPD; MED12; L3MBTL1; UBE2B; NFE2; RNF10; ZNF44; SP100; TRAK1; PLAGL1; SCMH1; TRIM22; PHF20; CREB3L2; HMGA1; CEBPA; ELF3; HMGB2; BAZ2B; MECOM; GTF3A; HBP1; SMARCD3; PNRC1; EMX2; CALCOCO1; HLF; HDAC6; ZNF665; ZNF264; TP53; CREG1; LITAF; MXI1; ZNF652; ZNF22; FUBP1; INSR; ZNF43; SALL2; YBX3; ST18; HDAC9; RBM39; ZBED2; KDM5D; PBX1; PBX3; ZNF160; HOXD1; SNAI2; MEIS1; FOSB; POU2AF1; BCL11A; NCOA2; HEY1; ZSCAN18; MTA1; GATA6; ZMIZ1; NFE2L2; ZNF331; DAXX
Down-regulation 22 ATF5; CLOCK; RNF141; SMAD1; HHEX; ZNF274; NR2F6; WWTR1; MAFB; VDR; EGR2; DRAP1; TEAD4; PIR; STAT4; JUNB; PITX1; FLNA; JARID2; VGLL4; ASCL1; NR1H2