Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06739 Wz-4002 GSE70138 CD34 Human 24h 10uM EID0033
Types Number Response transcription factors
Up-regulation 74 PPARG; BMI1; NFIL3; TDRD3; HLX; COPS2; SMAD6; DDIT3; MITF; LPIN2; UBE2B; NCOA3; TBX2; SERTAD2; PURA; TSC22D1; USF2; TCF12; RNF10; MXI1; TCF4; DNAJC1; TFEC; SREBF1; ATF4; CREBL2; NFAT5; SMAD7; BANP; CARHSP1; ELF3; NR1D2; ZBTB38; BATF; MTDH; MSX1; HAND1; KDM5A; FOXO4; PITX1; SKI; CREG1; YBX1; KAT6B; ZNF267; PHF1; IRF5; TOB1; TRIM22; GATA6; NCOR2; KLF6; ATF7IP; KDM2A; IRF8; JUN; NRBF2; SIAH2; TSC22D3; MED1; MBD2; ZMIZ1; EYA2; TSC22D2; ENO1; KLF2; ZEB2; TRIB3; HTATIP2; HOXB7; MAF; ATF3; MAFB; TOX3
Down-regulation 88 MYBL2; XRCC6; WDR77; HMGB1; BRCA1; MED14; CBX5; HDAC1; PTTG1; HMGB2; FOXM1; RUVBL1; CHD1; NFE2L3; WWTR1; PSMC3; CSDE1; UBE2L3; SMARCA1; CCNA2; MTF2; AES; SUV39H1; THAP10; HHEX; ZSCAN18; HMGA1; TLE4; ZNF394; HDAC9; CALR; SMAD1; CTNNB1; ZMYM2; MYBL1; TCF7L1; ZNF544; NFE2; CENPF; RNF138; NANOG; MYCL; TEAD4; DLX2; LHX2; PBX1; RERE; ZEB1; NAB1; NR4A2; ZNF273; ZBTB18; ILF2; EZH2; MYCBP; ZNF532; ETS1; ZNF195; FOXE1; LIN28A; TFDP1; BCL11A; ZNF512B; PBX3; NR1H2; ZNF239; ZIC3; EN1; NKX3-1; HMGB3; IRF6; PEG3; TFAP2A; PLAG1; DAXX; SUB1; BACH2; TAL1; ID4; RAD21; SATB2; TBX3; ZBED2; LOXL2; KDM5D; MYB; CDK2; ZNF586