Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06728 Gsk-1059615 GSE70138 CD34 Human 24h 3.33uM EID0033
Types Number Response transcription factors
Up-regulation 255 TAF12; SATB1; UIMC1; SSBP2; PNRC1; SNIP1; HMGA1; ZNF354A; RFC1; CHD3; BAZ2B; POU3F1; HDAC4; ERG; KLF7; HIVEP2; L3MBTL1; TBP; FOXO4; BTAF1; MED23; BCL11B; ZNF83; ZSCAN32; PPP1R13L; HOXC6; ATF2; RCOR1; ZHX2; KLF9; MXD3; MED12; STAT6; HBP1; EZH1; CDK9; NAB1; GATA2; TRIM22; MECP2; SSX1; RFX5; JUP; PHF1; ZNF184; PHOX2B; PAX9; MEN1; TAF1C; UBE2B; GTF3A; HOXC10; ING1; ZNF467; TSC22D1; THAP4; ARID1A; PCGF3; ZNF468; NKRF; RNF10; CEBPD; RARA; SERTAD2; CALCOCO1; HDAC6; ZBTB1; DBP; CIC; ID4; CD3D; MAML1; ZNF133; ELF4; MNT; NFKBIB; BRD7; ARID3B; BACH1; HMGXB4; ELK3; ZFHX3; ZBTB43; CREBL2; MED15; CREBZF; SP100; ORC2; HIPK3; PAXBP1; ZNF516; CARF; PBX2; HOXC4; AFF1; MED17; JARID2; NPAS2; YBX2; MEIS1; TAF1D; MLLT10; HDAC7; TRAK1; C1D; ZNF75D; CBFA2T2; TULP4; HSF1; PHIP; FOSB; CIZ1; ERCC3; RFX2; MZF1; BRD4; CAMTA1; SOX12; PSPC1; RBBP4; WWP1; OVOL2; SALL2; ELK4; CITED2; CREB5; SSBP3; INSR; BCL3; HDAC5; SKI; LPIN2; TBL1XR1; TEAD3; SREBF1; BRWD1; ZNF580; ZNF267; ZFHX4; ZNF34; MLXIP; MEOX2; HIPK1; PDLIM1; PLAGL1; HOXB2; ZBTB16; CUX1; EYA2; KLF3; ZNF33B; EGR3; SHOX2; FOS; AGO2; KAT8; PRMT2; MAFF; BTG1; ZNF239; NFE2; NR4A1; CREB1; NEUROD6; MEIS2; FOXO3; ZNF227; ETS2; ISL1; TCEA2; TFEB; MBD2; TGFB1; NCOR2; TRPS1; FOXD1; NR4A2; TSC22D3; ARID4B; RLF; NR0B1; SUMO1; SMAD1; BRD2; HIC2; NR3C2; ZMYM2; CBX7; TOX; TAF10; MECOM; MTA1; IFI16; NCOA1; ZSCAN31; KLF6; VGLL1; PBX1; HMBOX1; SOHLH2; BAZ1A; TAF9B; SP110; ZNF432; FOXA1; FOXN3; EHF; ELF1; SAP30; CNOT6; ARID5B; HOXB13; PCGF2; ZNF117; IRF1; NFIB; KMT2A; TGIF1; MYC; CREB3L1; ZNF189; CREG1; TFAP2A; PEX2; PAWR; ZNF165; RUNX3; TCF7L2; CNOT3; BHLHE41; RSF1; EYA1; ZNF12; PBXIP1; NCOA2; OSR2; MXI1; ATF3; REL; EMX2; TWIST1; NKX2-1; YBX3; DAXX; DLX5; ZEB2; LOXL2; ERBB4; SOX13; HTATIP2; ZMIZ1; KLF2; TBX3; TFAP2C; ZNF331
Down-regulation 67 PARP1; RAN; XRCC6; ADRB2; WDR77; ZNF274; NFE2L1; RUVBL1; ACTL6A; TFAM; PSMC3; MED27; MYBL2; NR2F6; FOXM1; ATF5; PCBD1; PTTG1; CENPF; GATA4; BRCA1; PRKDC; BIRC2; CCNE1; ZNF544; ZNF140; ASH2L; TRIM29; RBM14; CEBPA; RXRA; SFPQ; PITX2; ZSCAN18; EDF1; EN2; BATF3; CTNNB1; ZBTB18; BCLAF1; PROX1; CTBP2; ETV5; ILF2; TRIM16; PUF60; ENO1; VGLL4; SMAD7; C1QBP; TAF7; SUV39H1; CALR; LEF1; ZNF146; ZMYND8; SOX10; SCAND1; REPIN1; ZIC1; NEDD8; NUP62; TXNIP; NELFB; MAGED1; MAF; ESR1