Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06709 Ibrutinib GSE70138 CD34 Human 24h 0.04uM EID0033
Types Number Response transcription factors
Up-regulation 25 EZH2; RB1; ZBTB38; PSPC1; PTTG1; SMARCD3; CENPF; PITX1; HHEX; KDM5A; AFF1; ZMYM2; FLNA; HDAC6; SALL1; HTATIP2; TGFB1; PBX1; PDLIM1; CREG1; RBPMS; INSM1; MAF; NR1H2; MAGED1
Down-regulation 34 KLF4; ZHX2; AEBP1; MLXIP; NR2C1; ID4; CBFA2T3; SOX9; ZNF423; MTA1; PAWR; ERBB4; CD3D; PAX5; TCF7L2; ZBTB18; ISL1; DLX5; ZNF232; KLF10; TWIST1; ASCL1; MXI1; DLX2; NKX2-1; ZMIZ1; YBX3; NR2F1; SPDEF; POU2AF1; ZNF331; MEIS2; NFKBIA; TOX3