Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06707	Ibrutinib	GSE70138	CD34	Human	24h	0.37uM	EID0033

Response Information :

Types	Number	Response transcription factors
Up-regulation	61	RB1; ZNF468; WWTR1; AIP; CENPF; SMAD1; DNMT3B; BRD3; ELK3; FOXJ3; EZH2; PSPC1; TSC22D4; MED24; IL16; NCOA4; HOXC6; ZNF148; HLTF; PTTG1; ZNF443; ZMYM2; BRD8; RBPMS; SLC2A4RG; ZBTB38; REPIN1; POLR2A; DDX5; ING3; CBX3; BMI1; PTRF; DNAJC1; TRIM22; TFEC; SCAND1; HOXB7; SMARCD2; ZMIZ2; TRIP6; ZBTB20; CEBPA; NR1D2; TXNIP; WHSC1; YWHAB; SP110; NR1H2; KLF2; IRF8; CREG1; FOSB; MED1; NR2F2; TRIM28; NFIB; MAF; HTATIP2; MAFB; ZEB2
Down-regulation	101	ZNF654; E2F5; ZNF423; ATF4; PKNOX2; TAF1A; SOX3; AFF2; TRIB3; HIPK2; FOXA2; ZNF770; AEBP1; SSX1; AR; BCOR; NPAS2; ZHX2; MAFF; PBX1; ARNT2; PAWR; YBX3; TOX; ZFP69B; CCNH; ZNF215; WWC1; RBFOX2; ERBB4; HDAC9; RARG; TP63; FOXF2; FOXF1; CUX2; TBX1; BRWD1; ZNF232; PBX3; TAF4B; MEIS1; SOX17; JUN; HIPK1; ISL1; KLF13; REL; DLX5; SOX11; CREB1; BRD4; CDK2; FEZF2; NFE2L3; HIC2; HOXD1; KLF10; LIN28A; OSR2; PRDM14; HEY1; PEG3; BACH2; SOX13; CERS4; CREM; PLAG1; MECOM; IRF6; ZBTB16; ZIC3; SMARCA1; ZNF117; NCOA2; MEIS2; BNC2; ETS2; MYBL1; EPAS1; TFAP2C; ARID5B; ETS1; TCF21; SPDEF; TWIST1; CALR; NR2F1; POU4F1; ZNF331; TFAP2A; ZFPM2; NFATC4; NKX2-1; DLX2; TGIF1; SATB2; ATF3; SNAI2; MKL2; DAXX