Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06705	Ibrutinib	GSE70138	CD34	Human	24h	3.33uM	EID0033

Response Information :

Types	Number	Response transcription factors
Up-regulation	45	PTTG1; FOXM1; HIVEP2; RB1; TXNIP; EZH2; POLR2A; PPRC1; ZBTB38; ING3; SMARCC2; ELF5; KDM5A; NR1D2; MYT1L; MED1; TRIM22; ARID1A; ZNF544; SND1; BRD8; ZNF148; RLF; TRIM28; KDM5D; HNRNPD; NR2F2; ZMIZ2; CTR9; PA2G4; ZMYM2; KDM2A; SMARCD2; TP53; ZNF217; MSX1; TLE4; MAGED1; ZBTB18; ZFP36L2; RBPMS; KLF2; YWHAB; CREG1; ESR1
Down-regulation	62	USP16; ZNF654; FOSL2; E2F5; SOX9; PAXBP1; TRIB3; SHOX2; NR4A3; MAFF; CCNH; LOXL2; ZNF281; DACH1; WNT4; FOXN3; NPAS2; ST18; TWIST1; PCGF2; ILF2; FOXA1; NFE2L3; WWP1; VDR; ZBTB1; PRRX1; NR3C2; CREB3; BRWD1; SOX11; MEIS1; PLAG1; KLF4; NFE2L2; DAXX; HOXB2; PBX3; GATA6; BHLHE41; ETS1; SNAI2; NR2F1; MECOM; BNC2; ZEB1; SALL2; ZIC1; ZFPM2; CUX2; EGR2; TGIF1; SPDEF; MEIS2; HIC2; TBX3; FOXF2; ZNF331; ZMIZ1; ATF3; TFAP2A; MYBL1