Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06677 Bosutinib GSE70138 CD34 Human 24h 0.37uM EID0033
Types Number Response transcription factors
Up-regulation 53 DMTF1; SMAD1; CBX5; PTTG1; ID4; SUPT5H; SMARCD3; HOXA10; SMARCC2; MITF; ZMYND8; HMGB2; HDAC7; ELK3; HMGA1; CHD3; PBRM1; HOXB2; HNRNPD; REPIN1; CENPF; NR1D2; ZNF589; KLF6; RBBP7; CCNE1; TBL1X; KLF2; NFYC; CEBPD; YWHAB; ZNF587; KDM5D; MYC; MSX1; IRF8; KMT2A; ZNF274; BBX; TAF10; MXI1; ZBTB20; HTATIP2; ASCL1; ZEB2; PBX3; HOXB7; NR1H2; SOX17; TRIM28; DNAJC1; MAGED1; CREG1
Down-regulation 57 TRIM24; CD3D; MNDA; AFF2; BLM; MED17; ZBTB16; SOX3; CCNH; BRIP1; TGS1; PRRX1; SIX2; ANKRD1; ST18; SOX9; KLF13; ZEB1; PAX5; SMARCA1; FOXN3; POU2AF1; CUX2; CRYM; NR2E1; RERE; YAP1; BACH2; HOXD1; TCF7; RUNX3; E2F8; PAX6; POU4F1; ZIC3; ZNF232; LOXL2; NKX2-1; SATB2; NR2F1; HIC2; BAZ1A; TP63; TRIB3; MYBL1; EPAS1; FOXF2; TBX3; TFAP2C; MKL2; NCOA2; IRF6; DLX2; ZMIZ1; CDK2; FOXG1; RBPMS