Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06675 Bosutinib GSE70138 CD34 Human 24h 3.33uM EID0033
Types Number Response transcription factors
Up-regulation 129 MNAT1; PDLIM1; ATF4; ZFHX2; MEF2C; ID1; ZNF768; MED25; INSR; BRD4; SAFB; SIX1; SIN3B; ZNF205; SUPT3H; SUPT5H; EHMT2; HES1; ZNF358; ERBB2; ASXL1; BARX1; WDR77; HIF3A; OVOL2; HMGA1; APBB1; SMAD6; TAF5; MED12; CEBPD; BRD2; EYA2; SOX15; TFDP2; CIC; ZNF580; PTRF; KDM5C; URI1; TFCP2; KDM4C; CEBPG; THAP10; SUPT6H; ZNF516; SIX2; MEIS2; ZNF536; CREB3L1; AES; MAML1; MED16; ZNF444; PHF1; SP2; ID4; CENPB; MYRF; SATB2; KLF5; SOX13; MZF1; GATA6; PPP1R13L; PBX1; TRIM16; SOX9; DDIT3; CIZ1; CHD7; JUP; NR2F6; SNAI2; SOX2; CNOT3; HIPK2; SALL1; ISL1; SSBP3; POU2AF1; ELF3; TCF12; CARM1; HOXB13; TCF21; PLAG1; FOXO4; TFEB; NKX3-1; DACH1; PHIP; CBX7; RBFOX2; ASCL1; SMAD7; NELFB; FOXA2; WWTR1; ZBED2; GATAD2A; TGFB1I1; BNC2; PCGF2; HDAC9; CITED2; SOX17; EYA1; INSM1; NR4A1; DLX5; ZSCAN18; TP63; AEBP1; IRF6; SIX3; LIN28A; PIR; ERBB4; ZNF423; TGFB1; TBX3; FOXF1; ETS1; EPAS1; MECOM; ESR1; TRIB3; NFE2L2
Down-regulation 43 PCBD1; RAN; RB1; CDK7; TFAM; MBD4; ZKSCAN7; CCNC; DNMT3B; EGR3; NEDD8; C1QBP; LPIN2; HDAC6; CARHSP1; NCOA4; KAT8; TBX2; BAZ1A; DDX5; APEX1; ATF1; RNF4; ENO1; MAFB; MED13; LEF1; SPIB; YWHAB; NFKB1; EGR2; YBX1; PUF60; NUP62; CREG1; LITAF; EDF1; TWIST1; GTF2A2; NFKBIA; TP53; NR2F2; ZIC1