Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06670 Bix-02189 GSE70138 CD34 Human 24h 1.11uM EID0033
Types Number Response transcription factors
Up-regulation 70 EED; TLE1; IRF7; RELB; STAT1; PURA; ABL1; SAFB2; SP110; TCF15; SNW1; RBBP7; NONO; ZNF302; TSC22D4; FOXO3; ELK1; SP100; KMT2B; MAX; FLNA; ZNF358; MAGED1; SUV39H1; POLR2A; BCL3; IRF9; ELF1; TADA3; SF1; BATF; HDAC7; TFEB; REPIN1; EYA2; BRD8; ZMIZ2; CEBPA; FOXO4; LEF1; KDM5D; MAZ; IRF4; SOX10; JUNB; CTNNB1; EZH2; KMT2A; NELFB; ZSCAN18; NFAT5; RUNX3; WHSC1; MTA1; CARM1; KLF2; TP53; ZBTB18; HIRA; MSX1; EDF1; TSC22D2; TRIM28; PDLIM1; MAFB; MAF; HTATIP2; NR1H2; NR2F2; ZEB2
Down-regulation 55 MED21; TOX; HHEX; SOX11; RNF138; ZFPM2; REL; E2F5; PBX3; CDYL; TCF21; ZNF165; TCF12; ZNF423; ZNF195; DAXX; CREB3; NANOG; CREM; TCF7L2; KAT6B; GTF2I; IRF6; WWP1; TAF9B; LITAF; ARL2BP; PEG3; RBFOX2; ZNF33B; CREB1; SUMO1; ETS2; MECOM; BNC2; NFYA; ZNF232; MKL2; TOX3; PLAG1; CUX2; NFE2L2; ASCL1; CDK2; TRPS1; KLF10; JUN; POU4F1; ETS1; INSM1; BHLHE41; FOXG1; MYBL1; TRIB3; ZNF331