Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06645 Xmd-885 GSE70138 CD34 Human 24h 3.33uM EID0033
Types Number Response transcription factors
Up-regulation 127 IRF7; SRCAP; TRIM24; PNRC1; SPIB; HHEX; CUX1; IRF9; MED25; CBFA2T3; ZIM2; SMARCB1; KLF9; MLXIP; CREB3L2; ARID3A; MED15; LITAF; ZFHX4; ZHX2; YBX3; CBX6; NR0B1; KLF7; TCFL5; SIX2; ZFHX3; SIX3; SIM1; NFE2; THAP7; LEF1; NFATC4; TFDP1; OSR2; ZNF467; HIVEP1; RORC; GRHL2; HMBOX1; TULP3; SMARCD3; PEG3; MKL2; HIPK2; TCF7L2; ELK4; CTBP2; HIRA; BACH1; ZKSCAN1; HEY1; KAT2B; ELF4; JUP; REL; BACH2; SMAD3; TCF12; TERF2; DLX5; SSBP3; NR2E1; MECOM; TOB1; STAT1; PBXIP1; TBL1XR1; SUMO1; NR2F1; IRF6; MYBL1; SIX6; SOX9; ARID5B; BCL11A; TWIST1; CREG1; ZNF74; VPS72; TAL1; TBX1; DEK; FOXG1; CD3D; PAX6; MYC; KLF4; BCL6; CBX7; UBE2L3; PRRX1; JUNB; CDK2; LOXL2; FOXO1; TRPS1; SOX2; HOXC10; FOXD1; PEX2; SHOX2; ERBB4; RBFOX2; EPAS1; HIC2; ATF3; ZEB1; ZBTB16; CUX2; ZFP36L2; DLX2; TRIB3; SPDEF; RAD21; NFKBIA; TOX; ZMIZ1; DAXX; CALR; ZNF331; FOXF2; POU2AF1; SNAI2; NR2F2; ZNF423; ZIC1
Down-regulation 63 PUF60; CEBPA; RBM14; HMGB1; SNW1; ZNF329; SSRP1; ELF5; SMAD7; DNMT3B; HMGN3; HTATIP2; PDLIM1; EGR3; BMI1; NELFB; BASP1; KAT7; ZNF593; ENO1; PCBD1; ZNF274; MYB; UBP1; BRCA1; MAGED1; ID4; ARID4B; SUV39H1; ATF7IP; KDM5D; EDF1; SMARCA4; MED24; NR1I2; ING3; KMT2A; ZNF432; EGR2; YWHAB; AFF1; SAP18; SFPQ; NR1H2; RLF; ZNF587; SCAND1; MAF; GATAD2A; WHSC1; PTRF; TRIP6; BHLHE41; RBPMS; DACH1; TRIM28; JARID2; ZBED2; TP53; TSC22D2; ESR1; MAFB; MEIS1