Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06642 Vorinostat GSE70138 CD34 Human 24h 10uM EID0032
Types Number Response transcription factors
Up-regulation 197 CCNC; UBE2B; TSC22D3; STAT1; FOXJ3; MKL2; HMG20B; IKBKAP; TBP; BACH2; HLTF; ID1; CDK7; NR4A3; TCEA2; TLX3; PNRC1; TERF1; MNX1; TGS1; NR2C1; DLX4; CREBZF; NR4A2; FOXC2; SALL2; ATOH1; APEX1; MED23; NFIL3; ITGB3BP; ZNF589; ZNF711; HIF1A; THAP10; PEX2; ZNF576; ZNF7; POU4F1; CDK2; SUPT3H; NPAS2; CCNH; ZNF22; HSF2; MYT1; IRF4; SNAI2; SIX1; MYCBP; ZNF107; ZBTB25; NCOA3; CARF; NR3C2; BTF3; CREB3; E2F5; CREM; CRY1; WWTR1; ID3; ADNP2; PQBP1; ZNF215; SOX4; PKNOX2; TLE1; PAXBP1; TBL1XR1; MYT1L; SUPT6H; TCEA1; ILF2; ZIM2; FOXO3; ZNF331; ZNF224; CDYL; HDAC3; EED; YBX1; HBP1; ZNF273; EGR2; RNF4; MYRF; ESRRG; BCL6; SOHLH2; NR1H4; RUVBL2; TAF4B; SOX9; RHOA; SATB2; MEN1; ADNP; TFDP2; FOXC1; CRYM; ETV5; NRBF2; PBX1; NCOA4; LITAF; NR2F2; SMARCA5; TSC22D1; TFDP1; WNT4; ZNF623; TAF1D; CBX7; TOB1; ZNF165; RFX5; GMNN; TCFL5; TLE2; JAK2; IRX5; SOX10; PEG3; MXI1; ENY2; MED17; SP140; L3MBTL1; MED13; SALL1; HDAC4; PURA; ZNF354A; HOXB13; CREB3L2; PITX1; NPM1; ARNT2; ZBTB20; MEOX2; SMAD4; SMARCD3; WWC1; ST18; THAP1; PSIP1; CAMTA1; TAF9B; PRKDC; TRIP6; ZNF232; CREG1; SREBF1; FOXO1; CREBL2; TGIF1; ZFP36L2; TULP3; RUNX3; NR2F1; ECD; NR4A1; TCF7L2; TFAP2A; YBX3; KDM5B; HEY1; PAX6; PSMD9; SOX13; BHLHE41; TCF7L1; FOXF2; KLF9; ZKSCAN1; DLX2; OSR2; FOXG1; CHD7; INSM1; CTR9; TWIST1; ZNF43; HIC2; ARID4B; ZBTB16; POU2AF1; ASCL1; ERBB4; ZBED2; TRIB3; HHEX; TOX; MSX1; LEF1; MECOM
Down-regulation 160 CEBPA; VGLL4; TP53; XBP1; SMARCA4; SUV39H1; WHSC1; SPI1; MYBL2; DNAJC2; PCBD1; RBM14; BRCA1; IRF7; NUP62; CENPF; SF1; TFEC; ELF4; IRF5; FOXM1; SREBF2; ZNF335; BCL3; RBM39; PMF1; REPIN1; GATAD2A; TBL1X; KMT2B; MTA1; ZNF467; MAF; ZNF710; TADA3; DNMT1; JUND; MYB; HDAC7; SAP18; ZNF274; STAT6; MED16; GTF3A; HDGF; SCAND1; DDX54; RUNX1; LYL1; ZNF787; POLR2A; CEBPG; TRIM28; PHF8; ZBTB7A; GATA2; NCOA6; ZBTB18; ZBED1; BHLHE40; KDM5D; CLOCK; MAFG; MAZ; HLX; CNOT3; PSPC1; CEBPD; BAZ1A; ZNF394; CTCF; TAL1; CTBP1; NCOR1; SP100; RLF; BRD4; USF2; CHD3; RNF6; EYA2; SIAH2; PATZ1; ZNF580; RBPMS; SIRT7; NFE2; NFE2L1; MLXIPL; HMGB2; STAT5A; TGFB1; NR1H3; TFEB; ZMIZ2; BANP; PPRC1; KLF11; SUPT5H; BCLAF1; TSC22D4; HSBP1; NELFB; CIC; FOXK2; SP3; PCGF2; ZNF148; MEF2A; HMGA1; ATF4; AFF1; HMGB1; ZMIZ1; SMARCB1; OVOL2; EHMT2; ZMYM2; PRDM2; MAFB; JUNB; ZSCAN18; IFI16; ZMYND8; RREB1; E2F3; ESR1; KLF4; FOXF1; ELF1; NAB1; FOSL1; TGFB1I1; ATF5; KLF10; MEIS1; TRIM22; DEAF1; FOXD1; MYCL; MED24; KLF2; AEBP1; KLF6; ZNF281; NFATC1; LOXL2; TFAP2C; MNDA; BNC2; PIR; ZEB2; HDAC9; TCF4; SMAD1; MAGED1; JUP; NFATC3; NRIP1; SATB1