Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06630 Idelalisib GSE70138 CD34 Human 24h 0.04uM EID0032
Types Number Response transcription factors
Up-regulation 126 HMGA2; NR2F6; MYBL1; UBE2B; POU1F1; FOXI1; ZNF257; TERF1; SCAI; TRIM22; ZNF81; PBX1; TCEA1; CDK7; ZNF22; SOX11; VPS72; HSF1; PEX2; FEZF2; ZNF157; NR5A2; FLI1; ZNF124; SIM1; ZNF135; SUB1; BPTF; ZNF440; PAX4; COPS5; NFATC4; TFAP2C; TGS1; ZNF232; LHX1; ZNF141; ZNF492; SIX6; E2F8; TRIB3; VEZF1; FOXF2; MNDA; SP140L; NFE2L3; NR1H4; HDGF; SIX3; POU2AF1; NCOA2; EN1; CARHSP1; CUX2; YAF2; TWIST1; SOHLH2; HHEX; CDYL; TFEC; MYT1; ARNT2; E2F5; ENY2; ZFPM2; PITX2; ID4; TAF9; TOX3; ID1; CBFB; TOX; SALL1; TDP2; POU4F2; NR2F1; RREB1; BCL6; ZNF423; CCNC; NPAS2; ID3; RBBP8; CAMTA1; EMX2; ZIC3; ZNF623; ZIC1; TGFB1I1; IFI16; PAWR; NHLH2; RNF138; MBD2; LMCD1; STAT4; ARID5B; TGFB1; SALL2; ZEB1; SMAD4; TFAP2A; IRF8; LITAF; TCF7L1; RAN; DACH1; HMGB3; ZNF217; OSR2; WWTR1; TRPS1; ST18; ZNF91; ZNF331; SNAI2; LOXL2; NR4A2; PEG3; NEUROD1; CHD7; NKX2-1; KLF5; PSIP1; ESR1; BHLHE41
Down-regulation 100 TCEA2; ZNF443; ZMYND8; CIZ1; MTF1; ZHX3; ZBTB18; NFE2L1; ZNF282; HAND1; KDM2A; PDLIM1; CARM1; ENO1; TRIM28; BRCA1; NELFB; POLR2A; EYA2; SUV39H1; SF1; FEV; RNF141; TP53; TSC22D4; PLAGL2; BLM; SERTAD2; DDX5; ZZZ3; BAZ2B; SMARCA2; RUVBL2; RORA; SMARCD2; ELK1; HSF2; BBX; LYL1; ZBED1; SAP18; ZNF3; NKX3-1; ZNF468; SND1; STAT5A; PHOX2A; MXD4; ZNF432; FOXO4; ZNF211; MAGED1; ARID1A; CHD8; MAFG; SSRP1; CTR9; HMBOX1; FOSB; YWHAB; PHIP; ATF3; ZNF134; IRF1; EHF; RBL2; RNF6; SSBP2; MTA1; HMGB2; KLF11; SCAND1; BCL3; TAF10; FOXC1; ZBTB38; SMARCA1; TSC22D1; ERG; HMGN3; BHLHE40; INSR; BRD4; HOXB7; HOXC6; ZNF281; TFDP2; ZBTB16; TBL1X; KLF6; SMAD1; FOXG1; ARID4B; PIR; NFATC3; CREB1; HOXB6; MYB; JUP; ADRB2