Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06628 Idelalisib GSE70138 CD34 Human 24h 0.37uM EID0032
Types Number Response transcription factors
Up-regulation 114 SUV39H1; NR2F6; EPAS1; ARL2BP; BACH2; GBX2; FOXF1; TGIF1; VPS72; TRIB3; ETS1; NKX2-5; TP73; NEUROG2; NFATC4; HHEX; SUB1; RARB; SOX21; NR2F1; EMX1; FOXA2; ERF; POLR3C; ZHX2; ELK4; ZNF512B; ZNF529; FLI1; FOXI1; PAWR; ISL1; NR0B2; PRRX1; SUPT4H1; PTRF; ZNF165; TAF4B; CDK2; ZNF215; ZBED2; SOX11; ARNT2; CBFB; PEX14; CUX2; SKIL; MEIS2; NPAS2; SOX17; TFDP1; FHL5; CAMTA1; ZNF140; SATB2; ERG; SOX3; GATA6; TRIM22; EN1; ZNF623; FOXF2; PBX1; ESRRG; ILF2; TCF21; VGLL1; HMGB1; TFAP2A; FOXG1; TP63; TBL1XR1; NR5A2; MEOX1; MKL2; TCF7L2; SLC2A4RG; HLF; TOX3; TGIF2; MEOX2; TRPS1; ZFP36L2; ID1; TCEA1; HBP1; SOX9; ZNF232; DAXX; ID2; SOX13; ENY2; ZEB1; ID3; HEY1; C1QBP; WWTR1; TRIM29; ZNF532; ELF3; SNAI2; ERBB4; MNDA; PBX3; ZFPM2; LOXL2; HDAC9; HOXB2; SMAD4; ZBTB20; HOXD1; IFI16; NFIB; ID4
Down-regulation 89 IRF7; HDAC2; SMARCA4; ABL1; WHSC1; XBP1; KAT7; SND1; TRIM28; ZBTB11; PURA; MSC; USF2; ZNF3; HDAC7; SMARCA2; SMARCD2; KDM2A; NUP62; RNF141; RBM14; SREBF2; CLOCK; PTTG1; BASP1; JARID2; MAGED1; HTATIP2; FOXO4; MAF; NCOR2; CHD3; EDF1; BANP; TAF10; FOXL2; EZH2; NAB1; BRD4; SAP18; TFDP2; BCL3; POLR2A; ZNF302; DNMT3B; RLF; DBP; URI1; GATAD2A; SCAND1; TCF25; AFF1; MEF2A; PRKDC; ZMIZ2; RREB1; TSC22D2; FLNA; BCL11B; RXRA; HLTF; CTR9; AEBP1; MAZ; MED1; TOPORS; ARID1A; ZBTB18; JUNB; TSC22D1; HOXC6; TBL1X; MSX1; TGFB1; NKX3-1; PIR; BRD2; ZIC1; RELB; ZEB2; WT1; PSIP1; NFATC3; MYB; SATB1; ADRB2; ESR1; CREB1; GATA3