Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06606	Osimertinib	GSE70138	CD34	Human	24h	0.04uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	67	MTF2; IKBKAP; ZZZ3; NFRKB; BRIP1; EGR1; TMF1; FOXE1; AHR; BCL10; BLZF1; MED13; ZNF721; FLI1; HIPK3; REL; PRDM10; HIPK1; ZNF611; RBPMS; SUPT3H; ZNF224; CERS6; NR1I2; ZNF91; HHEX; KMT2A; ZNF665; PSMC3; ID2; TAF9B; ZMYND11; ZNF160; UBP1; ZNF44; SMARCA2; ZNF430; MLXIP; ZEB2; ERG; ETS2; ZNF512B; PAWR; DMTF1; ZSCAN18; LEF1; ID1; MED1; TFAP2C; HOXD1; ZNF652; ZHX2; NR4A1; NR4A2; INSR; BNC2; ZNF131; PITX1; ELF5; KAT6B; MAFB; THAP11; ZEB1; WT1; SATB1; PSIP1; CREB1
Down-regulation	39	HDAC6; HDAC2; NKRF; NFE2L2; ITGB3BP; HDAC7; CBFB; HIVEP2; PAX5; PCGF2; BCLAF1; SMAD7; INSM1; HIPK2; IRF6; ETV4; BCL11A; SAP18; TBX3; PRRX2; MECOM; NFAT5; ZSCAN31; EYA2; FOXC1; YBX3; FOXO1; NFATC3; CRYM; SMAD1; BTG1; TRIB3; MSX1; SOX9; ID4; TOX3; MAF; RBBP8; ZNF423