Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06605	Osimertinib	GSE70138	CD34	Human	24h	0.12uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	45	HSBP1; ZNF24; BCL6; FOXN2; THAP7; LZTR1; ZNF12; LMCD1; PFDN5; KLF9; DNAJC1; AHR; NAB1; PSPC1; BAZ2B; BTAF1; TCF25; TSC22D1; ETS2; BASP1; HMBOX1; TOX3; ENO1; LITAF; SATB2; ID1; HTATIP2; KDM5D; HEY1; KLF4; NFATC1; ZNF532; HMGB3; SOX9; TCF4; TXNIP; HIRA; RBPJ; INSM1; PIR; TBL1X; TRIM29; TRIM16; PBX3; ATF5
Down-regulation	94	CIITA; BACH2; POU4F1; NKX2-5; LEF1; TAL1; HOXD9; PLAGL2; ZNF419; ETV5; ZNF107; DYRK1B; NCOA2; RFX5; TAF4; EMX1; SOX17; WT1; HOXD10; RBL1; ZNF334; ETS1; PITX2; HOXD3; MNDA; CBFA2T2; PRKDC; PHOX2A; IFI16; SIN3B; TERF2; HOXD11; FLI1; TBX21; MECOM; SP140; ATF4; ZNF551; KLF1; E2F8; NR0B1; POU2AF1; SIX1; CBX4; TFAP2A; ZNF302; COPS5; HOXB7; FOXF2; HOXB13; SP2; EYA2; ZNF32; TBL1XR1; RERE; EMX2; GATA6; MYBL1; NFATC3; GTF2IRD1; HOXC4; SALL2; HOXD1; TP63; NR4A2; TAF10; CD3D; SIM2; TFDP2; LPIN2; CHD7; DEAF1; NKX2-2; TGFB1; MXI1; SOX11; TOX; NFE2L3; BHLHE41; BCL11B; TERF1; E2F5; EGR2; THAP11; MEIS2; HOXC6; ZKSCAN1; DACH1; PSIP1; TRIB3; ZFPM2; ERBB4; ZNF131; E2F2