Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06602	Osimertinib	GSE70138	CD34	Human	24h	3.33uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	EGR1; RUNX1; AES; MECP2; NFIC; PFDN5; TFAP2C; HIPK1; ZNF512B; ATF3; ZNF468; AHR; ADNP2; TSC22D2; ID2; CREBL2; HIVEP1; FOXF1; MED13; REL; BRD4; SHOX2; ZNF12; KLF11; NCOR2; STAT5A; EMX2; DDIT3; FLNA; ZNF217; CHD8; MITF; ZNF430; KDM5D; CITED2; ST18; IRF9; HHEX; PHF20; SATB2; CREB1; ETV5; TSC22D1; TCF4; SOX13; ZKSCAN1; LITAF; SOX9; BHLHE41; TFAP2A; TXNIP; JUP; ATF5
Down-regulation	59	PTTG1; BACH2; RB1; CENPF; EZH2; ACTL6A; PA2G4; TAF10; HMGB2; IRF4; CBFB; NR1I2; CDK2; SAP30; CALR; HOXA1; MYCBP; ZNF226; POU4F1; BCL3; RFX5; TBX21; FOXO1; PAX5; PITX2; HMGA1; SAP18; GFI1; PSPC1; SPIB; HNRNPD; SATB1; ZNF22; ZNF83; MSX1; BAZ1A; MYBL1; HOXC4; SSX1; IRF6; C1QBP; MBD2; ZBTB20; LEF1; DACH1; HOXC6; HOXB7; KLF5; NFATC3; ZBED2; SMARCA1; CHD7; IFI16; WT1; PSIP1; NFIB; ESR1; PEG3; GATA3