Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06568 Bms-777607 GSE70138 CD34 Human 24h 3.33uM EID0032
Types Number Response transcription factors
Up-regulation 125 MEF2C; TSC22D3; ZNF586; ZNF419; TTF2; ZNF304; JAK2; UBE2B; ZNF778; ZSCAN5A; ZNF211; NR2C1; SMAD3; ZNF33B; ZNF165; ZNF12; LHX2; FLI1; GBX2; ZNF135; ZNF7; KLF15; REL; GMNN; ZNF551; ST18; VPS72; RNF4; ZNF141; HESX1; SIX3; RFX2; ATN1; ARNT2; HDAC9; ZNF134; ACTL6B; NANOG; FOXN3; ZNF467; ARID3B; ZNF140; RBPMS; SMAD4; ZBTB25; SOX18; ZFHX3; ESRRG; ARID5B; DLX4; TRIB3; ZNF532; ARL2BP; CAMTA1; BLM; TBX1; TGFB1; CXXC1; WWC1; ZIC3; ZNF215; CCNC; ZNF544; SALL2; CDK2; SMAD6; NR1H4; SP140; KLF3; KLF2; NR5A2; ZNF268; STAT4; PBXIP1; CREBL2; BNC2; KLF11; JUNB; MXI1; MYT1L; DAXX; MYT1; ZNF665; MTDH; AHR; SOX13; HOXD1; TDP2; ANKRD1; LIN28A; ZNF43; ZNF117; CREM; HBP1; CITED2; NFATC4; ZFPM2; ZSCAN18; ZFP36L2; ELK3; KLF7; NR4A2; NCOA2; TOX; ZBTB16; RERE; ZNF331; TCEA1; CTBP2; MEIS2; CRYM; TFAP2A; FOSL2; LITAF; NFE2L3; ZNF217; LOXL2; HEY1; ZNF91; ATF3; SOX11; IRF6; TRIM29; ID4; PSIP1
Down-regulation 58 TP53; RBM39; YBX1; TAF10; HMGB1; SAP18; RYBP; ZFP36L1; CENPF; KAT6A; ZMYM2; PTTG1; MSX1; HMGXB4; ZZZ3; GATAD2A; HMGB3; BAZ1A; NR2F2; RBBP7; RNF6; FOXL2; SIAH2; RCOR1; TFCP2L1; POLR2A; KAT6B; BCOR; ZNF410; OVOL2; MAFB; LEF1; SCAND1; TSC22D2; ZBTB38; MAZ; FOSB; EYA2; WWTR1; HOXC6; MYB; JARID2; EGR3; MYCL; MEIS1; AEBP1; TBL1X; DMTF1; CHD7; TSC22D1; NFATC3; ARID4B; POU2AF1; ESR1; HOXB6; CREB1; MECOM; GATA3