Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06553	Ibrutinib	GSE70138	CD34	Human	24h	0.37uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	87	DRAP1; FOXJ3; SUB1; HMG20B; IKBKAP; CCNA2; MAML1; REST; EZH2; UBE2L3; CREB3L1; AR; PBXIP1; KAT6A; TRRAP; RHOA; HOXC10; SMARCD2; HMGA2; HLTF; HOXB13; TGFB1I1; SETD2; TAF6; NFAT5; HMGXB4; GTF2A2; TCF12; MED13; DPF2; PMF1; MAGED1; MNDA; FOXO3; NKX3-1; SALL1; CEBPD; BCL3; RBPMS; SLC2A4RG; CDK8; PITX1; MED24; TRIM22; JUNB; SMARCD3; SMAD5; CBX6; WWTR1; TLE2; PSIP1; AES; FLI1; STAT6; HIRA; TRIP6; KDM5D; MEF2A; PLAGL1; BRD3; RERE; NCOA1; VPS72; NR2F1; CITED1; RUNX3; LEF1; ZSCAN18; ARID1A; OSR2; CALR; EMX2; BCL11B; TCF7L2; TLE4; KLF10; BMI1; ARID4B; HOXB2; PBX1; ZBTB18; IRF8; PEG3; CD3D; MSX1; SATB1; TXNIP
Down-regulation	95	ZNF721; MAFG; TAF1A; USP22; CREBZF; ZNF160; NR2F6; CREG1; SP100; MTF2; PHIP; ZNF611; NANOG; THAP4; TOB1; TDRD3; ELF4; TCEB2; CNBP; TAF1D; BRCA1; TRIM33; MYBL1; ZNF573; ZNF654; TFDP1; E2F3; MAF; ZNF195; HAND1; SOX3; TGIF2; ZNF587; LIN28A; ZNF281; JUN; VDR; MDM2; CIR1; CCNH; ZNF84; BRWD1; ESR1; HMBOX1; TDP2; PQBP1; SOX2; DMTF1; NR1I2; FUBP1; ELF1; HTATIP2; DAXX; MEOX1; WWP1; MED14; RFX5; EYA1; ZMYND8; ERBB4; THAP11; ZNF217; ZNF44; INSM1; ZNF423; PRRX1; TERF1; ENY2; HMGA1; ZFP36L2; NKX2-1; TP63; ARNT2; TRPS1; KLF5; TRIM29; MECOM; MAFB; DACH1; WWC1; ZIC1; NR4A1; ATF3; ID3; NFATC3; MBD2; HOXD1; ZBED2; ZBTB16; CHD7; TWIST1; SNAI2; ZNF131; PPARG; NR3C1