Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06552	Ibrutinib	GSE70138	CD34	Human	24h	1.11uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	CRK; MNAT1; HOXC10; ZNF146; TULP4; ZNF224; BNC2; ADNP2; HOXA10; MAFF; EGR1; NR2C1; ERG; SOX15; HOXA11; PREB; TAF7; SERTAD2; ZNF426; FOXD1; ZNF665; ZNF394; ZNF136; BHLHE41; EYA2; ING2; LMCD1; SMAD5; AHR; CRY1; HIVEP2; RLF; ZNF430; PURA; CBFA2T3; ELF1; MYC; HOXC6; CDK8; ZNF432; SIX2; ZNF721; SNAI2; EYA1; PIR; NR4A2; ZNF160; TRIM22; ZSCAN18; FOXE1; KDM5D; SIX1; ZBTB38; ZBED2; CITED1; NR4A1; OSR2; ZNF652; SMARCA2; SMARCD3; ZEB2; KLF6; ZNF264; AEBP1; CTNNB1; RBBP4; EMX2; HMGN3; RUNX3; TBL1X; PTRF; ELK3; ZKSCAN1; TRIM16; SATB1
Down-regulation	89	ZFP36L1; ZNF212; NR1I2; CARM1; ARID5A; MKL2; ZNF711; TRIM33; MTF1; RCOR3; RBL1; PMF1; ZBTB16; JUND; ZBTB44; ZNF148; SMAD1; MEIS1; PLAGL2; HAND1; SUMO1; MECP2; SCAND1; GATAD2A; HIPK1; NFIC; NAB2; PHOX2B; ATF5; SOX11; BRIP1; CERS4; PPARGC1A; THAP7; MAFB; ZNF107; HIPK3; POU2AF1; CAMTA1; VPS72; ZBTB20; KAT6B; MYBL1; ZNF410; NR5A2; HLF; TFAP2C; LPIN2; FOXF1; EDF1; BRD4; FOXG1; NFATC3; NFIB; LEF1; SOX10; ZNF281; WWC1; HOXB5; TERF2; DLX2; ZBTB18; EGR2; TOX; SIAH2; ARNT2; FOXO1; LITAF; HOXB6; PITX1; ZNF423; TFAP2A; NKX3-1; ZEB1; ID3; HEY2; TCF7L1; TCF7L2; SMARCA1; PEG3; ZIC1; CD3D; MEIS2; CREB1; CHD7; MXI1; TLE4; HEY1; PSIP1