Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06551	Ibrutinib	GSE70138	CD34	Human	24h	3.33uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	RFC1; BRD7; RB1; HOXA10; TCF12; HMGA2; MEF2A; HOXA11; IRF2; NFRKB; OLIG2; SOX11; MNDA; TFEC; TCF7; CEBPD; JAK2; ARID5A; NCOA4; SKI; BLM; SATB2; ZSCAN18; PCGF2; SMARCA2; FLI1; HMGN3; ATF3; ZNF189; MEIS2; RBPMS; KDM5D; CREM; CAMTA1; BMI1; EYA1; PSIP1; RHOA; TAF9B; ZEB2; EMX2; ELK3; LEF1; SATB1; BHLHE41; NKX2-2; TOX; FOSB; EGR2; DACH1; GATA6; WT1
Down-regulation	60	NR2F6; ZBTB7A; BTG1; ETS1; PCGF1; KLF13; TOX3; CDYL; TRIM33; EPAS1; ZNF3; FOXO1; CARM1; CCDC59; ZNF593; SIX1; SCAND1; CTBP2; BASP1; USP16; NR1D2; MED13; FLNA; TCF3; PAWR; PQBP1; RARG; HMGB3; RYBP; TBL1X; ZFHX4; SMAD1; HLF; PAX5; ERG; ZNF195; PLAGL1; CUX1; ZBTB20; TFAP2A; DDIT3; BNC2; NFATC3; CRYM; ZNF91; CREB3L2; KLF5; POU2AF1; MAF; HIC2; HOXB6; DLX5; TCF4; MITF; SNAI2; TSC22D1; PDLIM1; ID3; NKX2-1; ZNF131