Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06550	Ibrutinib	GSE70138	CD34	Human	24h	10uM	EID0032

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	DRAP1; NFKBIB; DEK; DR1; COPS5; ZNF589; PURA; DDX17; TCEA1; NFIL3; FOXO3; PLAG1; TGIF1; TFEC; EMX2; COPS2; SREBF2; HOXA11; ADRB2; ZBTB11; BBX; CTBP2; LMCD1; MXI1; KLF11; TFDP1; DAXX; HTATIP2; BASP1; TXNIP; KDM5D; HMBOX1; NCOA2; NR1D2; ZFP36L2; CREG1; TOB1; ATF6; FOXN3; SNAI2; BTG1; ELF5; TRIM22; TLE4; ZBTB18; OSR2; ATF3; KAT6B; PSIP1; MYBL1; KLF9; ID4; CREB3L2; NFATC3; ATF5
Down-regulation	57	WHSC1; NKX3-2; MTA1; PLAGL2; IRF7; SOX17; RNF4; CARHSP1; CNOT2; ZFP36L1; ELF4; EZH2; ZNF468; RLF; POLR2A; HOXA5; SIX1; TRIM24; FOXG1; ZNF200; CTBP1; ZNF195; CAMTA1; NKX3-1; MSX1; AEBP1; FOXF1; SOX9; FOSL2; L3MBTL1; ZNF83; CTR9; TEAD4; PITX1; SHOX2; IRF8; SLC2A4RG; TSC22D1; ERBB2; KLF10; HOXB7; CALR; HES1; MECOM; AFF1; HOXD1; NR4A1; RBPMS; FLNA; SOX11; INSM1; ZFPM2; NR2F1; MAFB; EGR3; NFIB; WT1