Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06501 Tivozanib GSE70138 CD34 Human 24h 0.04uM EID0032
Types Number Response transcription factors
Up-regulation 76 SAP30; TBX2; TBP; TTF2; UBE2B; RFC1; SMAD3; HMG20A; ZNF292; HBP1; TAF1A; TAF11; TBL1XR1; BRD7; BRIP1; CHD9; ARID3A; ATF2; BACH1; KAT8; ZNF688; TAL1; MNDA; PAXBP1; MNT; MYB; HOXB6; DBP; ID4; TRIM22; EGR1; PBX1; PEX2; ZNF32; SUMO1; HIPK2; BHLHE41; CUX2; VPS72; MXI1; EGR3; ZNF195; ID3; PRRX1; NR4A2; TCF7L2; MECOM; SMARCD3; TWIST1; TRIP6; TDP2; MAFB; SALL2; NFE2L3; BASP1; AFF1; ZNF423; ZKSCAN1; NR2F1; MEIS2; CREG1; TFAP2A; EGR2; FOXO1; SATB1; TRIB3; RBBP8; ZEB1; ID1; MYRF; ERBB4; LEF1; KLF5; NFIB; WT1; NFATC3
Down-regulation 58 BACH2; ZNF136; PTTG1; TRIM24; DNMT3B; RUNX1; CREB3L1; PFDN5; CCNE1; EN2; MLX; AATF; MAGED1; TSC22D2; FOSL1; SMAD7; BBX; NR3C2; BAZ1A; YBX1; RBM39; SMARCB1; PEG3; AEBP1; HNRNPD; NFATC1; URI1; NKX3-1; SCAND1; INSM1; NEUROD1; ZNF410; TOX3; MITF; HMGB3; SPIB; MAF; SHOX2; ZBTB38; CBFA2T3; STAT4; ZNF264; ELF1; ZNF91; HMGN3; MEOX2; FOXA1; JUNB; CTNNB1; ARID4B; PAX5; TBL1X; ZSCAN18; ZNF586; JUP; MYBL1; GATA3; NR3C1