Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06496 Tivozanib GSE70138 CD34 Human 24h 10uM EID0032
Types Number Response transcription factors
Up-regulation 230 PAX8; UBE2B; ZNF165; SIX3; SOX21; MBD4; TCERG1; PBX1; CEBPD; ZKSCAN3; ZNF75D; ZNF345; NEUROD6; ZNF154; ZNF33B; ZNF117; NR1H2; PNRC1; ZNF195; POU6F2; NFATC4; CHD2; TULP2; RSF1; ASH1L; TCF7L2; HSF4; MED20; TP73; NCOA2; MECP2; VENTX; PBXIP1; TBX5; VPS72; CSDC2; ZNF85; EMX1; ZNF273; ZNF141; BCL6; HOXB1; ZBTB44; POU2AF1; ZSCAN32; ZNF550; TFCP2; BRWD1; PAX7; HBP1; ETS1; RARB; TGIF1; CIITA; BHLHE41; GATA2; TRIB3; CDK2; FUBP1; PRDM14; TSHZ2; NKX2-5; ZNF665; FOXH1; ZNF770; MECOM; PBX3; SOX3; ZNF589; SUMO1; TCEA1; CREB5; ZFP36L2; ZNF529; ZFHX3; DDX17; TRAK1; ERBB4; CARF; ING4; TDRD3; ZNF423; MNX1; FEZF2; HMGB1; CCNC; ZNF354A; NANOG; ZNF654; TRIM22; ZNF682; ZNF180; FOXE1; ARL2BP; FOXF2; WWC1; ARID3A; GCM1; NR1H4; TAF4B; TFAP2A; POU4F1; HESX1; REL; PIAS1; ARNT2; ILF2; ZNF224; CBX2; PRDM1; TAF9; IKZF3; ZNF250; PRDM10; ZHX2; NPAS2; TBL1XR1; MXI1; ZNF200; ZNF331; SOX18; ZNF107; BACH2; ATF3; FLI1; PAXBP1; CDIP1; CUX2; PHIP; TSC22D1; TOX; L3MBTL1; USP16; IRF9; CSDE1; SRY; ZNF215; TDP2; NFE2L3; POLR3C; SALL1; SPDEF; ZBED2; HOXA11; CITED2; FOXC1; MED17; SREBF1; HOXD1; EMX2; PRMT2; KLF7; HOXD3; NR5A2; RARG; KLF11; TFAP2C; HIVEP2; EPAS1; ZNF22; ARID5B; ZNF304; PEX2; BACH1; SALL2; CNOT6; SIX6; ZNF623; BRIP1; DLX5; PMS1; VGLL1; ZNF232; RBBP8; MEIS2; TERF1; TCEA2; ZMYND11; ANKRD1; SOHLH2; MNDA; BCL11A; CALCOCO1; SOX13; NR2F1; SMARCA1; CAMTA1; HOXC4; PFDN5; MED14; PSMC3; YBX3; E2F5; HHEX; APEX1; SOX11; PHOX2B; SP140; RFX5; ID2; ZNF239; PAWR; TERF2; DDIT3; CREB3L2; LITAF; SOX17; GTF2A2; FOXO1; ZFHX4; HDAC9; GATA6; CREG1; IFI16; ISL1; ID3; FOXG1; LOXL2; DACH1; PLAGL1; TRPS1; NKX2-1; KAT6B; PAX5; MYBL1; TCF7L1; TRIM29; KLF6; SATB1; KLF5
Down-regulation 114 VGLL4; KAT7; RBM14; MLX; ZNF329; DRAP1; BIRC2; SMARCD2; GATAD2A; NELFB; EDF1; USF2; BAZ1B; SMARCA4; TP53; TRIM28; TSC22D2; SUV39H1; SF1; PMF1; TADA3; ZNF274; NUP62; EZH2; BRCA1; ENO1; EGR3; RLF; DDX54; ZNF468; MTF1; HDAC1; TCEB2; NFE2L1; BRF2; PHF2; USP22; YWHAB; NR1D2; ZIC1; MAGED1; SMAD7; BRPF1; ZNF3; HDGF; MED21; STAT5A; PHF8; CRY1; ZBTB18; SSBP2; MAFF; ZNF593; CARM1; HSF2; MAF; BANP; ZNF606; SREBF2; INSM1; CLOCK; CENPB; ZBTB11; NFYC; PUF60; RUNX3; FOXL2; TOX3; BRD4; HTATIP2; BCL11B; RBBP5; TAF10; MEOX2; SSRP1; IRF3; CDK8; BCL3; ZNF134; BCLAF1; KLF2; TRIM16; SCAND1; MED1; AHR; IRF7; MED24; THAP11; JARID2; PIR; UBP1; KLF10; ZMIZ2; EHF; BMI1; SMAD5; CHD8; ADRB2; AEBP1; MAZ; DNAJC1; SFPQ; ERBB2; FOSL2; ELK3; NR2F2; SMARCA2; CD3D; BASP1; ZBTB38; PSIP1; MAFB; TLE4; CREB1