Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06487 Xmd-885 GSE70138 CD34 Human 24h 0.37uM EID0032
Types Number Response transcription factors
Up-regulation 114 MYBL2; NR1H2; RBBP7; HES1; MNAT1; BCL3; KLF2; ASH2L; BCL11B; TTF2; TAL1; CBX7; CD3D; ETV6; ING2; ZMYND11; MECP2; ASCL1; BRD7; HOXD11; SMAD3; E2F2; RBPMS; SNAI1; HOXA1; ARID4A; CARHSP1; HOXB7; TOX; ZEB2; STAT3; SIX1; ZNF222; COPS5; TCF21; WDHD1; LEF1; RCOR1; HIVEP2; MSX1; GATA2; HOXA11; BCOR; ID4; DBP; EMX2; NR0B1; YWHAB; PEG3; IRF2; PAXBP1; AATF; NCOA4; MBD2; TGFB1; OLIG2; NKX2-1; DNAJC1; SALL1; DLX5; HOXA10; NFKBIA; GFI1; KAT2B; FLI1; NCOR2; HOXC10; NPAT; SMAD6; L3MBTL1; TCFL5; ELF1; FOXC1; C1QBP; NR1D2; NKX2-2; MXD1; HDAC4; STAT4; IRF8; PRKDC; SP2; TAF9B; ETV5; MYB; MED6; FOXE1; HEY2; RHOA; KDM5D; NFAT5; MAF; AFF1; CREM; SIAH2; BAZ1A; ZBED2; CREG1; MED1; NFATC1; CHD7; EGR2; WT1; HDAC9; AEBP1; ATF6; RUNX3; BHLHE41; IFI16; SATB1; HOXC6; PIR; MAFB; NFATC3
Down-regulation 130 ABL1; VGLL4; ZFP36L1; CTBP2; CRYM; SFMBT1; THRA; BASP1; HMGA1; ZNF562; DNMT3B; REXO4; FOXM1; ZNF91; ZNF35; IRX4; DEK; ZNF93; HMGXB3; PHOX2B; ZNF672; HMGB2; ZNF239; ZSCAN12; ZNF253; TFEB; NR1H3; HDAC2; SOX9; STAT1; ZNF611; MKL1; LDB1; SHOX2; TCF3; TAF11; MAK; TEAD1; ZNF195; PIAS4; KDM5A; ACTL6A; IRF7; ATF5; ZNF160; PCGF1; CSDE1; ZNF606; MXD3; HDGF; TULP3; ASXL1; ZNF573; ZNF3; ACTL6B; ZBTB17; CENPF; NELFB; ZNF500; ATF4; ATN1; ZIC3; CEBPG; EHMT2; GMNN; ZBED1; LYL1; TAF10; CHD8; THAP11; PCGF3; SOX11; ESRRG; PRPF6; FOXI1; ZNF544; SP3; SOX2; EHF; ZFHX4; COPS2; PPARGC1A; KLF4; LIN28A; PQBP1; NKX3-1; TCF25; MEIS1; ZNF117; TWIST1; RXRA; LOXL2; ZNF44; ZIC1; ZNF43; TGFB1I1; PHF20; FOXN3; BRD3; CCNE1; TBL1X; ZNF721; PAX5; BTG1; ZBTB18; INSM1; RBFOX2; DAXX; ZNF264; MYBL1; MXI1; IRF6; DEAF1; RBPJ; SNAI2; JUP; ARNT2; ZNF652; ZNF532; PDLIM1; TRIM29; MECOM; SMARCA1; TRIB3; TFAP2A; RBBP8; KLF5; TRIM16; PSIP1; NFIB