Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06480 Nvp-bgj398 GSE70138 CD34 Human 24h 0.37uM EID0031
Types Number Response transcription factors
Up-regulation 132 TAF4; RSF1; SOX13; TOPORS; BRD7; HMGB1; NCOA2; SAP30; PRMT2; NFYB; MED4; RBFOX2; EED; MEIS2; UBP1; UBE2B; SALL2; CRY1; POU4F1; PNRC1; RBBP8; YBX3; SMAD4; RNF138; ARID1A; MLLT10; MYC; RAD21; IRF5; ETS2; TRIM24; SMAD2; TDP2; TGFB1I1; SETD2; TGIF1; RFX5; AGO2; HMGB2; PRPF6; CREBL2; ZNF354A; MEIS1; PLAGL1; ENY2; TULP3; MAML1; YEATS2; NR2C1; FOXJ1; ZBED2; TCF7L2; CTR9; ATN1; NFIB; WWTR1; IRF2; MBD2; ADNP; C1QBP; BPTF; BAZ2B; TCF7L1; ZNF423; FOXN3; ZNF426; EHF; HIPK1; ZNF22; TCEA1; FUBP1; TOB1; ZBTB1; TCF12; ZNF195; MLXIP; BNC2; DEAF1; ZFHX3; TRIB3; RRN3; HSF2; INSR; SNAI2; PIR; TERF1; TFDP1; BHLHE41; MED21; SOX17; TCF21; FLI1; ZNF516; PHF20; CHD1; MEOX1; PSIP1; FOXF2; MECOM; ARNTL2; PBX1; ELF5; ZMYM2; KLF5; OSR2; COPS2; TRPS1; SUB1; POU2AF1; JAK2; WWC1; TFAP2A; CUX2; MXI1; BASP1; TOX; CREG1; LITAF; ZFPM2; HTATIP2; IRF4; ELF3; FOXF1; CRK; HDAC9; AHR; ARNT2; GMNN; KDM5D; ZBTB16; ZNF652; MAFB
Down-regulation 52 STAT1; FOSL1; MED27; PDLIM1; PREB; HNRNPD; STAT4; RUNX1; KLF2; TRIM25; ASH2L; UBE2I; TBX21; DLX4; SFPQ; BCL3; PITX2; SOX9; NELFB; CDK9; CENPF; RBL1; DLX2; HSBP1; BCL11B; RXRA; TBL1X; FOXG1; FOXL2; TSC22D2; NEUROD1; ZMIZ1; LOXL2; NR1D2; HOXC6; MSX1; MAGED1; TXNIP; FOXD1; NKX3-1; ZBTB18; TRIM16; NFATC3; RUNX3; GATAD2A; ZBTB38; ASCL1; MYBL1; HOXC10; SUV39H1; ZNF91; RELB