Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06467	Idelalisib	GSE70138	CD34	Human	24h	1.11uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	CDK7; NR1H2; MYC; PCBD1; HMG20B; PPARD; SUB1; SIAH2; SOX15; GTF2A2; PMF1; PBXIP1; ZNF576; RHOA; DBP; SETDB1; SLC2A4RG; NCOA4; ZNF146; HOXA11; MEIS2; ZNF337; ZNF384; MZF1; PRDM1; ZNF133; IRF8; SOX11; PITX1; MLXIP; USP21; HDAC5; IKBKAP; SIRT7; CDK8; WWTR1; MED24; PPP1R13L; TP63; ZNF629; PNRC1; ARID1A; RCOR1; SREBF1; RUVBL2; SIX3; TRIP6; VPS72; AR; TCF4; LITAF; TCF12; NFE2L1; CITED1; ATN1; KLF1; ATF7IP; PCGF2; TRIM16; RORA; YBX3; RXRA; MNDA; FOXD1; PLAGL1; MXI1; ARNTL2; IRF4; HIC2; FLI1; SSX1; IRF6; HBP1; THAP11; HHEX; BMI1; NR2F1; MEOX2; BASP1; ZNF512B; ARID4B; CREG1; HIRA; TXNIP; TLE4; FOXF2; PAX6; HOXB2; TRIM29; SOX9
Down-regulation	89	USP22; BRCA1; XBP1; SFPQ; E2F3; CCNH; CBFB; SF1; KLF2; ZNF721; PRRX1; AEBP1; CBX3; SP110; BRD7; TOB1; PQBP1; NFKB2; NFATC4; XRCC6; CNBP; TRIM33; WWP1; ZNF217; RBL1; BIRC2; VDR; FOXA1; LMCD1; ZNF593; PSMC3IP; SMARCA2; ZNF160; TBL1XR1; ZMYM2; TCF7; BRD2; ATF3; VGLL4; SP100; ZBTB16; TAF1A; PA2G4; WT1; AHR; INSR; PHF20; TFDP1; LIN28A; SCAND1; ZMIZ1; ZNF281; NR1D2; DACH1; HOXD1; CREB3L1; HMGN3; CTBP2; TGIF2; ZNF329; TOX3; EDF1; DDIT3; NANOG; ZEB2; ESR1; SMAD6; TERF1; ZBTB18; MYBL2; HOXC6; SMAD2; ID3; FLNA; EHF; BHLHE41; LEF1; ZNF587; ARNT2; NFATC3; ZNF423; ASCL1; HTATIP2; MYBL1; MYB; PEG3; SNAI2; ERBB4; PSIP1