Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06444	Osimertinib	GSE70138	CD34	Human	24h	0.37uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	MNAT1; ID1; HABP4; MEIS2; BBX; SETD3; HOXA1; TWIST1; HLF; YAP1; ING2; ID4; TAF7; HIVEP2; FOXC1; EPAS1; FOXO1; KLF5; ESR1; HMGB1; EYA1; TAF12; PRRX1; RARB; HIPK2; ZMYND11; KLF2; COPS5; RAN; MBD2; ID3; MSC; ELK4; SMAD3; SMARCA5; HEY2; ELK3; HIPK3; GATA3; HNRNPD; BHLHE41; RNF111; GLI3; DNAJC2; BAZ1B; ZNF22; RBFOX2; ZFHX4; ZNF423; PEG3; SNAI2; CDK9; CHD7; IFI16; NR1H4; MECOM; DLX5; ESRRG; BATF; POU2AF1; CCNE1; LHX2; KAT2B; ZBED2; CUX1; KLF9; TXNIP; MYBL1; WWTR1; NFAT5; KLF13; ZBTB18; SIX1; RXRA; RBBP8; RBBP7; HOXB6; SSBP2; ZEB2; TRPS1; ASCL1; SMAD7; HDAC9; ERBB4; LMCD1; NFIB; SOX17; IRF4; ZNF91; TCF7L1; PBX1; NR2F2; ZSCAN18; NFE2L3; AHR; SMAD5; TP63; ERG; BASP1; TCF4; NR2F1; HES1; ISL1; ZNF281; SMAD1; EMX2; TOX; SOX9; MAFB; NFATC3
Down-regulation	76	CIZ1; RREB1; MXI1; PCGF3; ATF3; ZNF668; ZFP64; TCF3; YEATS4; ZBED1; SFPQ; JUND; BRF2; FOXF2; MNT; PRPF6; RUNX1; ZBTB43; CASZ1; FOXM1; CIR1; ARID1A; ZBTB48; HDAC5; POLR2A; TRIM27; JARID2; MLXIP; CNOT2; SALL2; ZNF500; YBX3; DNMT3B; ENO1; NR2C1; TAF11; GATA2; ADNP2; HOXB13; HIPK1; CTBP1; TFAP2C; SREBF2; SP3; MAFG; NPAS2; SREBF1; TADA3; ADNP; FOSL2; ETV5; NFYC; REL; MITF; RORA; ZNF12; CITED1; TRIM29; IRF6; GATA6; TRIP6; NKX3-1; RUNX3; PLAGL1; CARHSP1; NR0B1; CD3D; TFAP2A; MNDA; HOXB7; LITAF; INSM1; EYA2; TBX3; PSIP1; NR3C1