Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06442	Osimertinib	GSE70138	CD34	Human	24h	3.33uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	48	NR1H2; CEBPD; ZBTB43; HDAC5; NFKBIA; GATA3; PBXIP1; JARID2; CREB1; NFE2L1; MSC; BCL11B; TOPORS; SMAD7; PAXBP1; ETS2; HIPK1; ISL1; AFF1; AEBP1; KLF7; NR1D2; CUX2; ETV5; REL; IRF7; ZNF12; FLNA; MYCN; HBP1; ATF3; DMTF1; NKX2-1; ZMIZ1; ERG; TXNIP; ID3; CD3D; TWIST1; TOX3; KLF9; LITAF; AHR; ASCL1; EHF; PSIP1; NFATC3; ATF5
Down-regulation	60	CREG1; BRCA1; NFE2; RB1; RBPMS; EN2; HEY2; WT1; MTA1; SUPT3H; RERE; SOX5; ZNF580; NR5A2; WNT4; MEIS2; RBBP7; DACH1; WWTR1; BNC2; FOXL2; ID4; TLE2; TRIM28; LMCD1; HLTF; ST18; PSMC3; TRIM16; PBX1; PA2G4; NPM1; MED24; CHD3; ZNF266; FOXG1; BACH2; HOXC6; MYBL2; GATA6; ZFPM2; C1QBP; PRKDC; NR1H3; CHD9; GTF3A; HMGB3; ELK3; HOXB7; HOXC10; HOXC4; OSR2; ZEB1; LOXL2; EMX2; ZBTB38; MYBL1; SUV39H1; ESR1; ZNF586