Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06433	Motesanib	GSE70138	CD34	Human	24h	0.37uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	KDM5B; MYC; YBX3; HMGB1; HOXA4; KLF5; FHL2; YBX1; PNRC1; HOXA10; HMGB2; RORA; OVOL2; EMX2; CRYM; CNBP; TLE1; CBX7; RCOR1; SNAI2; TRIP6; TRIM29; TP63; NPM1; HIVEP2; HBP1; PDLIM1; BHLHE41; OSR2; JUP; CNOT3; SIM2; SPDEF; HOXB13; TWIST1; FOXA2; ZNF654; PSIP1; ZSCAN31; CEBPD; BCL11A; TRIM28; TFAP2A; CREB5; ISL1; CCNE1; FOXG1; TRIM16; ELF3; RAN; HOXB6; CCNC; HOXA5; MEIS1; GMNN; LITAF; WWC1; TAF10; EHF; MXI1; ST18; TOX; PTTG1; FLNA; TSC22D1; PBX3; MEIS2; KDM5D; WT1; SOX17; EYA2; CITED2; ERBB4; NFATC3
Down-regulation	38	BIRC2; BRCA1; IFI16; NR2F6; ETS1; MEF2A; KAT7; EGR2; SMAD2; HOXC6; ZNF267; KLF2; TCF4; SCAND1; AEBP1; HTATIP2; TADA3; IRF7; NFYC; MED24; FOSB; TGFB1I1; ELK3; BCL3; BCL6; THAP11; MAFB; VDR; EGR1; TFEC; ATF3; GATAD2A; FOSL2; ZNF652; ZFPM2; EGR3; LEF1; ZNF586