Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06431 Motesanib GSE70138 CD34 Human 24h 3.33uM EID0031
Types Number Response transcription factors
Up-regulation 106 CD3D; RCOR1; SMARCD3; MYC; MAML1; MEIS2; BCL11B; KDM5A; STAT4; NFE2; TCEA2; TOX; PCGF3; DEAF1; SUPT3H; CEBPG; EGR2; PPP1R13L; ZFP36L2; ZNF195; BCL11A; SUPT5H; PLAGL1; NFE2L2; DBP; GLI3; TP63; TSG101; SMARCA1; ID1; SUB1; RNF4; SNAI2; PRDM1; TAL1; TFDP1; CNOT6; CTBP1; ZNF354A; ILF2; NFKB2; MBD1; ZBED2; GATA3; ERF; ETS2; NFKBIA; SLC2A4RG; KLF1; YBX3; NRBF2; RBFOX2; IRF1; ATN1; NPM1; MXI1; NFATC4; FOXF2; RORA; WWC1; MED21; TRPS1; KAT6B; NKX2-1; SOX11; TAF10; FOXO1; HBP1; TRIM29; CUX2; NR4A3; EMX2; ARNTL2; ZNF239; PHF20; ZSCAN31; CHD3; TFAP2A; LYL1; NCOA2; IRF4; LITAF; COPS5; TGFB1; ERBB4; GMNN; TRIM22; MEIS1; ARNT2; TLE4; LEF1; PDLIM1; JUP; ID3; ESR1; PEG3; HEY1; WT1; RUNX3; MNDA; BHLHE41; MECOM; CITED2; EHF; POU2AF1; MAFB
Down-regulation 67 STAT1; ADRB2; FOSL1; PARP1; PMF1; ING3; DRAP1; MED24; SMAD2; THAP11; DDX54; SMARCA2; KLF2; SND1; BARX1; TRIM32; HNRNPD; TOX3; CXXC1; SPIB; TCF15; JUNB; SMARCD2; NELFB; BCL3; OLIG2; HOXC6; ZNF160; SP3; KAT2B; AFF1; FOSB; LMCD1; KLF11; TERF2; ZMIZ2; ING2; EDF1; HOXC10; KLF4; ZMYND8; TOB1; TSC22D2; ZNF721; PBX3; INSM1; MYCN; SOX9; TCF12; ZBTB20; INSR; HOXB6; NEUROD1; MYCL; ZNF443; HOXB7; CHD7; NANOG; HTATIP2; ELK3; NR4A1; ZNF91; MAGED1; NFATC3; NR4A2; ASCL1; PSIP1