Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06413 Gsk-1059615 GSE70138 CD34 Human 24h 3.33uM EID0031
Types Number Response transcription factors
Up-regulation 180 ADRB2; SATB1; GABPB1; ATF1; PNRC1; TGIF1; PHF1; TSC22D1; MED4; NR1H2; ZNF467; RARA; TCEA2; ATF2; MAFF; MECP2; UBE2B; ETS2; KLF10; PHIP; HIF1A; C1D; CREBL2; BAZ2B; HMGB2; BRD2; RING1; BRD7; SATB2; RAD21; MED23; ENY2; HIVEP1; SOX4; RFX5; ELK3; BHLHE41; PCGF3; RSF1; ZNF423; PHF20; ZNF331; WWTR1; ZNF184; REL; FUBP1; SOX13; CDK9; TDP2; LOXL2; FOXO3; CBX7; ZNF165; TSC22D3; ERG; HHEX; HDAC5; TCF7L2; RFC1; NFATC4; UIMC1; HBP1; ZNF200; BTAF1; LITAF; SNAI2; SALL2; RCOR1; TCEB2; TAF12; ING4; PPP1R13L; NAB1; SP100; PBX1; FOXA2; PBXIP1; BCL11A; DEK; SMARCA1; PCGF2; FOXO1; BACH1; TOPORS; MYRF; SREBF1; ZSCAN31; TCEA1; L3MBTL1; IRF1; PQBP1; JUP; SOHLH2; RYBP; TAF9B; CEBPD; ATN1; KLF7; INSR; TWIST1; SMARCD3; VEZF1; PEX2; ST18; ID1; SAP30; NR3C2; COPS2; CREM; TOB1; PAXBP1; ARID4B; SOX17; SOX11; FOS; KLF9; NKX2-2; TXNIP; DAXX; BTG1; PLAGL1; ID4; TFAP2A; ZBTB1; ZMYM2; SUB1; AHR; MEIS2; HDAC4; PSIP1; TAF10; TERF1; ZNF217; ZNF652; BCL6; KLF2; ZBED2; HSF2; AFF1; RBM39; ZNF93; PITX1; COPS5; HOXA5; PDLIM1; BBX; ZFP36L2; MEIS1; HOXB2; HOXB6; GMNN; ZNF415; ATF3; ZMIZ1; BRD4; BMI1; TOX; HMGA1; HTATIP2; IRF7; WWC1; LIN28A; TBP; ZNF83; ZBTB18; HDAC9; ZNF665; FOSB; SOX9; HOXC6; SMAD7; MYB; CREG1; MECOM; EGR3; NR4A2; PEG3; ZNF91; ESR1; HES1
Down-regulation 61 RUVBL1; SFPQ; XBP1; WDR77; PCBD1; FOXM1; BRCA1; SPEN; ELF5; BIRC2; RUNX1; ENO1; PARP1; CHAF1B; ZNF274; LZTS1; GFI1; ZBTB24; NOC2L; RBL1; NKX3-1; RAN; XRCC6; RBM14; YEATS4; TRIM32; AEBP1; EZH2; RNF141; BCLAF1; CREB3L2; MYBL2; SPIB; GATA4; PRKDC; LEF1; BLM; CRYM; BRIP1; CENPF; TULP4; FOXL2; PA2G4; NR1I2; PUF60; MAGED1; BATF3; FOXC1; NR2F2; TRIM29; FOXG1; SUV39H1; PAX5; TFEC; MYBL1; ZNF512B; NFATC3; ASCL1; KDM5D; PBX3; ZNF586