Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06402 Doramapimod GSE70138 CD34 Human 24h 1.11uM EID0031
Types Number Response transcription factors
Up-regulation 109 HIF3A; BCL11A; HOXA5; MEIS2; BARX1; SMAD3; ZNF141; HINFP; CRYM; TEAD3; SOX13; CALCOCO1; PEX14; E2F6; ZNF146; NKX3-2; FOXF2; ENO1; ZNF667; CUX2; HDAC9; PRPF6; MYRF; MYCN; PBX1; BNC1; TRIB3; NFYB; SALL2; TCF7L1; ZNF140; PHF20; ZNF500; INSR; TCF21; ATN1; GRHL2; STAT4; L3MBTL1; KLF10; NPAT; ZNF202; BANP; FOXF1; CDK2; TCF7; ZNF529; TAF1A; TULP3; CBFA2T3; ZNF268; WWC1; CCNE1; RERE; FOXG1; ZFP36L2; ZNF536; MYT1L; NFE2L1; ID1; ZNF711; ZNF589; MED24; MKL2; EMX2; HOXB5; E2F8; SMAD1; NFE2; HIC2; ARNT2; LIN28A; ERBB4; ZNF43; MECOM; TFAP2A; ZNF423; RAN; ZSCAN18; HOXB6; SOX17; HMGB2; KLF6; TCF7L2; LEF1; IRF7; ZNF512B; TGIF2; ST18; ZNF329; ELF3; ID2; NANOG; GMNN; CREB1; ZNF232; POU2AF1; ZNF665; MAGED1; SHOX2; BRD4; HOXB2; TCF4; KDM5D; ZNF652; HEY1; ZNF91; MEIS1; ZIC1
Down-regulation 73 RUNX1; ZEB2; SMARCA2; RBL2; JUNB; CTCF; TLE4; BCL3; FOXD1; SMAD2; HTATIP2; SMARCD3; PIAS2; AHR; BTG1; HOXC6; NKX2-1; PBRM1; CNBP; NCOA4; NR1D2; DLX2; EBF2; MTDH; NR4A2; ZNF226; BCLAF1; IFI16; CHD7; ZNF24; MNDA; TULP4; GATAD2A; SATB2; TRIM22; BATF3; VDR; CREB3L2; C1QBP; NAB1; MBD2; SIM2; MEOX2; BMI1; FOXC1; TP53; NFAT5; FOXO1; ZNF124; FOSB; SIX1; SMAD4; MXI1; TOX3; HLTF; TAF10; TBL1X; KLF5; NFATC3; TRIM29; KLF9; PBX3; RBBP8; BAZ1A; INSM1; BASP1; EGR3; ASCL1; PSIP1; RELB; ID4; MAFB; ZNF586