Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06391	Ibrutinib	GSE70138	CD34	Human	24h	0.37uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	STAT5B; IRF4; PPARG; STAT5A; NR1D2; KAT6A; HMGB2; PLAG1; HLF; HIPK3; SAP30; TULP4; BATF; PTTG1; IKBKAP; CREM; ST18; CTR9; NR3C2; ZEB2; ENO1; DEK; ZMYND8; RUVBL2; BCL11B; ERG; HOXB7; SOX10; BATF3; PDLIM1; RUNX3; MAFF; SSX1; ELK3; NR4A2; LPIN2; ZBTB18; MED1; EPAS1; FLI1; CD3D; AHR; TOB1; PTRF; BMI1; PIR; PSIP1; HOXC6; MYB; NR2F1; MAGED1; JUP; TXNIP; BASP1
Down-regulation	70	STAT6; NFE2L2; LZTS1; MEIS1; ATF7IP; YBX3; E2F5; ZNF195; ZNF669; PKNOX2; ZNF12; CREB5; SMARCC2; CREB3L2; KLF7; BRD4; RBBP8; TSC22D1; TERF2; ZNF573; NFAT5; BACH1; WT1; CREBZF; KLF13; NFIC; KAT6B; ARNT2; E2F8; MYCN; CTBP2; GATA6; ZNF512B; ZNF423; ZNF84; ZNF83; ZNF43; NPAS2; PAX5; TRIB3; ZNF93; TCF7; FOXC1; ZNF124; PBX3; SP140L; KDM5A; TCF4; ESR1; EMX2; ZNF264; ZNF551; SMAD4; PAWR; GLI2; ZMIZ1; BCL6; GATAD2A; TFAP2A; ERBB4; ZNF430; MAFB; KLF6; NFATC3; MNDA; TRPS1; BHLHE41; ATF3; ID4; HES1