Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06390 Ibrutinib GSE70138 CD34 Human 24h 1.11uM EID0031
Types Number Response transcription factors
Up-regulation 44 E2F2; NFX1; NCOA4; GATA3; STAT4; RNF14; TRIP6; PIR; BATF3; TBX21; KAT2B; STAT5A; SUB1; AR; SOX13; ADNP2; TFEB; CITED1; PIAS2; SMAD2; MEIS2; NFE2; SMAD1; ESR1; TLE4; LYL1; BBX; EGR1; GMNN; MAGED1; ZNF516; EYA2; SMAD7; PLAGL1; RBPMS; FOSB; HOXD1; SMAD4; KLF6; NR4A1; PITX1; BASP1; MEOX2; CITED2
Down-regulation 61 DLX2; CNBP; ETS1; CUX1; CUX2; KAT6B; HMBOX1; PITX2; HOXC6; SPEN; KLF5; ZMYND8; HEY1; NCOA1; SIM2; HMGN3; LEF1; TERF2; BPTF; SOX9; RERE; SERTAD2; YAP1; HOXB13; NFAT5; EN1; NCOR2; TOX3; PHIP; ATF7IP; PBX3; PEX2; ERG; ZNF195; PAX5; NR2F2; BRIP1; PTRF; TRIM29; FOXC1; BACH2; ZNF281; VGLL4; PRRX1; NFATC3; CHD9; KLF11; DACH1; ARNT2; ZNF232; ZBTB16; ID3; MSX1; FOSL2; SNAI2; HES1; ZIC1; PSIP1; ZNF131; PEG3; ZNF586