Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06389	Ibrutinib	GSE70138	CD34	Human	24h	3.33uM	EID0031

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	SMAD3; BMI1; NR3C1; BTG1; KLF5; TMF1; NR1I2; RUNX1; HIVEP2; CRYM; MED23; TERF2; DEK; SIM2; BCL11A; TFCP2L1; OVOL2; FOXM1; CRY1; NR2C1; PPP1R13L; ETS2; CENPF; POU4F1; PAWR; MED1; KLF2; ERG; VDR; TGIF1; HMBOX1; BRD2; EYA1; KLF4; NKX3-1; HMGB2; SMAD1; TOB1; CTBP2; IRF6; TCF7L2; MECOM; BASP1; TOX3; COPS5; HTATIP2; SIX2; PTTG1; PDLIM1; RBPJ; HOXC6; ZNF652; ASCL1; TRIM29; NFATC3; ESR1; VGLL4
Down-regulation	102	ZFP36L1; WT1; MEIS2; SALL2; LZTS1; SMARCD3; SOX13; TRPS1; ADNP2; ZKSCAN5; GTF2I; TGFB1; PBX2; RARA; TRAK1; NR2F1; RBBP4; HMGN3; SAP130; RERE; SUPT6H; GON4L; SKI; EGR2; TRRAP; TAF9B; GLI3; TSG101; TLE2; CBX4; ZSCAN9; ZNF189; CITED1; FOSL2; CAPN15; SALL1; BCOR; ZNF24; ZBTB16; HIC2; LIN28A; BNC2; FOXN3; SHOX2; ZNF593; NKX2-2; SOHLH2; TFAP2C; E2F3; ZNF211; ZNF711; GTF3A; JARID2; SOX11; NANOG; SMAD6; HDAC1; ZNF217; RXRA; ARID5B; ZNF134; ZNF93; TRIB3; AFF1; PAX6; HOXB6; SMAD5; ERBB4; E2F5; DLX2; ZNF589; ZBTB18; ZFPM2; SOX9; MAFB; RBBP8; HDAC9; PBX1; TRIM22; ZNF512B; ARNT2; TLE4; HOXB2; NFIB; HOXD1; CHD7; MYRF; PAX5; KLF9; NR4A2; PEG3; FOXF1; IRF8; AHR; PBX3; CALR; TBX3; PSIP1; ATF3; HES1; GATA3; ZNF131