Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06363 Bosutinib GSE70138 CD34 Human 24h 0.04uM EID0031
Types Number Response transcription factors
Up-regulation 299 SOX2; NFATC4; ZNF623; DAXX; VENTX; PRDM14; ZNF345; ZNF75D; ZNF557; ZNF250; SALL2; CDK2; CRYM; ZNF154; TP73; FOXH1; ZNF239; TBX1; ZNF74; ZNF682; TBL1XR1; SOX13; ZIC3; FOXF2; ZNF215; ZKSCAN4; MDM4; PAX1; TULP2; ZNF219; TEAD3; ZNF550; NFYA; ZNF273; RFX1; TCF3; CNOT6; POU6F2; ZBTB44; BRWD1; STAT2; IRX4; ZNF573; TDP2; ZNF7; ZNF362; TAF4B; TEF; BACH2; CDK7; TCEA2; AGO2; ZNF749; ZNF33B; ZNF286A; HIRA; BCL11A; NKX2-1; TRIB3; RORC; ZNF814; BNC2; ZNF141; ZNF343; ZNF480; RORB; SP4; THRB; SETDB1; RARG; HEY1; FOXI1; NKRF; MYEF2; ZNF549; TAF1A; ETV6; CBL; ZBTB3; TCF7L1; ZKSCAN3; ZNF235; ZNF232; VPS72; HSF1; AFF2; NEUROG2; ACTL6B; EMX1; ZNF195; TP63; ZNF816; FEZF2; POLR3C; ZNF507; SOX18; ZNF22; GTF2I; ZNF264; CUX2; MAK; HIVEP1; PPARA; THAP7; SCAI; ZNF85; ABT1; ZFP69B; KLF3; ILF2; FOXJ3; NHLH2; SPDEF; RBFOX2; ZNF133; ZNF257; ELK4; TAF9; ATOH1; ZNF696; PPP1R13L; LIMD1; ETS1; NR2F1; ZNF589; DMTF1; SUMO1; HOXB5; ATN1; HIC2; HIPK2; ZNF184; BARX1; ZNF43; AR; PRDM12; CBX7; ZNF337; ZNF500; THAP10; ZNF180; CHD2; TCEA1; IRF9; PLAG1; ZNF165; SOX12; IRF6; TERF1; SUPT3H; ZNF529; IKZF3; THRAP3; GRHL2; BNC1; ZBED4; FOXO1; TLE2; XRCC6; ZNF135; TRAK1; ZNF654; REL; ZNF350; TFAP2A; ZHX2; PITX1; DDX17; CBX6; MLLT10; CAMTA1; ERBB4; NFKB2; CREBL2; SOX11; ZNF532; ZFHX4; L3MBTL1; ZEB1; MYCL; TULP3; CDIP1; GLI3; ZNF223; CITED1; PRDM2; ZFPM2; SIX6; ZNF423; USP16; TSC22D1; ZNF675; ZNF701; UBE2L3; HHEX; TCF7L2; WWC1; CNOT3; BCL6; RAD21; EPAS1; E2F5; TGIF1; LHX2; TGIF2; ZNF711; FOXA1; ZNF667; TFCP2; HOXB2; ZNF665; FOXA2; ZNF354A; GMNN; LIN28A; YEATS2; FUBP1; BHLHE41; ZNF304; RUNX1; SIX3; RAN; ZNF415; RCOR3; ZSCAN18; CSDE1; ZNF268; CBFA2T2; OVOL2; ZBED2; ST18; ZNF586; ARNT2; ZFHX3; TCF4; MEIS2; SNAI2; FOXC1; KLF13; NFE2L3; LITAF; PAWR; DLX5; ZNF44; ARID5B; HOXB6; ZNF611; ZSCAN31; CREB1; MYBL1; SOHLH2; NR4A3; NR3C2; APEX1; ZNF281; SHOX2; YBX3; TWIST1; TFDP2; ZBTB16; ZFP36L2; MKL2; KLF7; MYCN; RYBP; ZNF551; CEBPD; THAP11; TFDP1; PAX5; MXI1; AEBP1; ZNF12; PBX3; CTNNB1; ARNTL2; TFAP2C; NCOA2; SOX17; TRIM29; ID1; ZNF512B; BRD4; PAX6; NR2F6; GLI2; ZNF652; HDAC9; ZNF544; ATF3; FLI1; FOXF1; ZBTB20; SMARCA1; TRIM22; MECOM; CALR; POU2AF1; SMAD1
Down-regulation 106 BIRC2; XBP1; SAP18; NUP62; USP22; DRAP1; SMARCA2; CEBPA; USF2; EDF1; SMARCA4; MAGED1; ZMIZ1; POLR2A; PHF2; ZMIZ2; HMG20B; BCL11B; KLF2; MED1; NCOA6; SMARCD2; FOXO4; CHD3; TLE4; FOSB; NONO; KDM2A; RBM14; KAT7; SCAND1; ZNF226; ATF5; TMF1; BRD3; AFF1; TRIM28; ING2; ZNF593; GATA2; NR2F2; RNF6; RBPMS; EGR4; FOXO3; JARID2; HOXC6; NR1I2; WHSC1; DNAJC1; DDX5; FOXD1; SND1; ZEB2; WT1; ZMYM2; BAZ1B; TCEB2; PLAGL2; CTR9; NR1D2; ZMYND8; TP53; ZNF443; MAZ; AHR; SAP30; PIAS2; SMARCE1; RBBP7; HSF2; NELFB; BMI1; ERBB2; MSX1; ESR1; TAF10; TSC22D2; CITED2; NFAT5; TXNIP; ZNF217; SIAH2; JUNB; EGR3; SMAD2; KDM5A; HTATIP2; TBL1X; FLNA; GTF3A; BASP1; TOB1; SUV39H1; KDM5D; NR4A2; PIR; ZBTB18; FOSL2; MYB; PSIP1; MEOX2; NFATC3; MAFB; MAF; LEF1