Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06360 Bosutinib GSE70138 CD34 Human 24h 1.11uM EID0031
Types Number Response transcription factors
Up-regulation 71 IKZF1; TSC22D3; SAP30; BTG1; KLF2; HMGB1; SETD3; UBE2I; MYB; PAX5; SMARCA5; ING2; ZNF423; NR3C2; TERF2; FOXO1; HNRNPD; POU4F1; CDX1; CHD4; MYT1L; TAF9; INSR; TLE4; TXNIP; PLAG1; RELA; CREB3L1; ZNF148; SMAD1; ZNF281; RBFOX2; GATA6; BRD4; PITX1; ZFP36L2; ENY2; HMGB2; SNAI2; STAT4; E2F5; BRD2; TBL1X; MYCN; BACH2; TCEA1; RBM39; ETS2; TOX3; MAFB; ELK3; ZNF232; POU2AF1; KLF5; LYL1; TERF1; HOXB6; BASP1; FLI1; TBX3; VDR; ISL1; FOXF1; HMGA1; KLF9; PBX1; KDM5D; SOX9; TWIST1; HHEX; PEG3
Down-regulation 63 CREB3L2; SOX10; GTF2I; CBX7; TRIP6; ENO1; POU5F1B; RFX7; WWTR1; ZBED4; ZNF227; ADNP2; ZNF551; NCOR2; RUNX3; ST18; ZNF529; BRIP1; MED13; ZNF394; ZNF134; SERTAD2; TBL1XR1; TRIM28; HOXC6; HOXD3; YBX3; ELF5; IFI16; REPIN1; SSBP2; ZNF468; NR1H4; SALL1; RXRA; ZNF304; SP140L; ZNF211; EMX2; ZNF217; HMGN3; ZNF83; CARHSP1; ZNF432; ZNF224; TFAP2A; LIN28A; TSC22D2; BHLHE41; ZIC1; CITED2; LITAF; NFATC3; HTATIP2; EHF; TFAP2C; MAF; MAGED1; HOXC10; MYBL1; HES1; PSIP1; ID4