Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06359 Bosutinib GSE70138 CD34 Human 24h 3.33uM EID0031
Types Number Response transcription factors
Up-regulation 93 MTF2; NR3C1; TP73; FOXF2; ZBED2; BAZ2B; MECP2; ZSCAN31; ZKSCAN4; FOXF1; TDP2; TRIB3; NFATC4; PIAS1; HHEX; UBE2B; CREM; TCEA1; ARNT2; ID1; IRF1; ELF1; RNF6; PQBP1; NKX2-1; TOX; VPS72; ZNF331; HIPK1; SOX11; WWC1; ATF4; ERG; TSC22D3; RYBP; BCL11A; SMARCD3; TFAP2A; NFE2; ZNF140; PHF20; HOXD3; ENY2; MEIS2; MNDA; TULP3; WWTR1; NR4A3; REL; ZNF654; TCF12; BHLHE41; HBP1; HMGN3; ZNF423; TOB1; KLF10; DDIT3; TFDP1; DAXX; ZFPM2; SALL1; HOXD1; ID4; BRD2; BBX; DMTF1; INSM1; ZMYM2; LYL1; TRIM22; MYCN; PDLIM1; ZEB1; ZHX2; PBX1; HIC2; SOX9; TWIST1; ELK3; MSX1; NR4A1; GMNN; PITX1; LITAF; MEOX2; ZNF264; BASP1; CREG1; ATF3; WT1; SNAI2; MAFB
Down-regulation 38 ADRB2; DDX54; NR2F6; ENO1; NUP62; BRCA1; RBM14; ZHX3; BCLAF1; MAGED1; CENPB; SND1; CARM1; ELK1; DNAJC2; PREB; USF2; TLE1; PURA; ZBTB16; RERE; ZMIZ2; SMARCA2; NPM1; ZNF226; REPIN1; TADA3; TCF4; CTR9; FOSL2; PRKDC; SPIB; GATAD2A; ZIC1; NFATC3; ASCL1; PSIP1; GATA3