Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06357 Bix-02189 GSE70138 CD34 Human 24h 0.04uM EID0031
Types Number Response transcription factors
Up-regulation 58 TBL1XR1; TBX2; TAF9B; PKNOX2; IRF5; HIPK3; JUN; SOX3; GTF2I; TAF12; MEIS2; GATA6; TCF21; SOX10; TFAP2C; CDK2; AFF1; MYCN; E2F5; MLLT10; HDAC4; YAP1; URI1; FOXA1; MLXIP; HOXB13; TCF12; MYRF; PAWR; DNAJC1; BHLHE41; IRF4; BRIP1; NKX2-1; NR0B1; PBX1; ZSCAN31; WT1; WWTR1; EYA1; ST18; ZHX2; WWC1; TCF7L1; HDAC9; PSIP1; HMGN3; ZBED2; ZNF232; MBD2; PBX3; NKX3-1; PAX6; NFIB; TOX; POU2AF1; NFATC3; MYBL1
Down-regulation 66 MDM2; ETS2; DDX5; SFPQ; HLX; YWHAB; LOXL2; PLAGL2; YEATS4; SPI1; HAND1; POLR2A; ELK3; ZNF136; KLF2; SCAND1; CNOT2; PURA; DAXX; NPM1; TCF7; ZFHX4; MED1; ZNF430; PRKDC; ZNF160; ZNF91; HOXB6; HLF; ITGB3BP; ASH2L; NFE2; FOXD1; NR1D2; TOX3; ZNF611; ZNF587; ZNF652; TRIM22; SIAH2; ZNF468; KLF1; ZBTB18; VDR; DACH1; FOXO1; APEX1; EYA2; ESR1; HIRA; IFI16; BCL3; MEOX2; PITX1; HHEX; HEY1; ZEB2; PAX5; SHOX2; BASP1; MECOM; ASCL1; MAFB; PEG3; LEF1; HES1