Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID06354 Bix-02189 GSE70138 CD34 Human 24h 1.11uM EID0031
Types Number Response transcription factors
Up-regulation 106 STAT3; TXNIP; IKZF1; FHL2; KLF5; NFKBIB; PRDM1; PPARD; RUNX1; NKX2-1; ZNF263; TBX21; PLAG1; NR1D2; IRF9; CHD4; EPAS1; ZNF22; DBP; LHX1; NEUROG1; PMF1; HOXB9; HLF; RREB1; MKL2; ZSCAN32; ZMYND11; EMX2; EZH1; HIPK3; FOXA2; POU4F1; TGS1; PPP1R13L; TAL1; HMGA2; GTF2I; CARHSP1; YAP1; HMGB1; IRF1; RERE; CRYM; ETV4; TP63; RBBP5; RBL2; ZSCAN31; GTF2A2; ZBTB38; ARRB1; GATA6; BCL11B; SMARCA1; TULP3; CDYL; ZNF593; KLF10; CD3D; PTRF; IRF6; SMAD6; FOXO1; PITX2; DNAJC2; IFI16; BRD2; MED6; WWTR1; TCEB2; ING2; NR3C2; HMGB3; TCF7; PHF20; PAWR; HOXB13; SSX1; TFEB; HOXA10; NR2F1; TRIM29; POU2AF1; ZIC1; KLF1; MECOM; KLF9; MEOX2; AHR; IRF8; PSIP1; ID4; ELF3; NFE2L3; PIR; EGR2; ZNF432; TRIM22; JUP; MAGED1; LEF1; NFATC3; SMAD1; SOX9; VGLL4
Down-regulation 94 ATF1; RFX5; FOSB; FOS; THAP11; CREB3L2; HDAC5; WT1; YBX1; SOX12; SUPT3H; C1QBP; HMBOX1; CBFB; ZNF516; MYCL; CBX5; TFDP1; ZNF532; ZBTB18; INSR; CTBP2; BTG1; ZNF529; HTATIP2; VEZF1; DR1; HAND1; NR0B1; REPIN1; LMCD1; RUNX3; ZSCAN18; ISL1; SMARCA2; MTDH; BRD7; BAZ2B; DNAJC1; HMGN3; HHEX; DLX2; YWHAB; OLIG2; NKX2-2; EYA1; RAN; HMGB2; PFDN5; TBL1XR1; ZNF239; RBBP8; ZNF331; E2F3; MYCN; CREB5; PA2G4; CBX6; HOXC6; ZNF667; ZNF573; ESRRG; HDAC4; SIX2; CREB3L1; ZNF93; SPIB; ID2; FOXC1; ZNF302; ST18; ELF4; KAT6B; INSM1; ZNF329; NR2F2; EGR1; CHD9; RBPMS; FOSL2; IRF4; ATF3; FOXF1; TFEC; ZNF131; CITED2; MYBL1; ASCL1; RELB; PBX3; MEIS1; NR4A2; PEG3; HES1