Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID06041	Regorafenib	GSE70138	ASC.C	Human	24h	10uM	EID0107

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	XBP1; NFIL3; TRIB3; DDIT3; GABPB1; CCNH; CEBPG; TRIM33; HOXA11; TDRD3; POLR3C; RNF138; COPS2; HMGB2; SOX10; PSMC3; BBX; TOX4; MTF2; CNBP; RBBP8; FOXN3; SOX11; ATF3; BNC2; CITED1; CREB3; ZNF532; NPM1; ZNF267; ZNF410; ISL1; CTBP2; MITF; AFF4; TCEA1; CHD1; BACH2; TRIM24; PKNOX2; CCDC59; CSDE1; DR1; TDP2; ZZZ3; HOXD3; CCNC; GATA2; ARNTL; ZNF516; NR2F2; LMCD1; ESR1; ERBB4; BIRC2; IRF9; ZBTB18; APEX1; HNRNPD; IRX5; ZMIZ2; ANKRD1; TWIST1; ING3; ASCL1; NANOG; ID3; RYBP; ATF4; IRF4; TFDP2; ZNF211; CREB3L2; TOX; ELF5; ZHX2; HDAC9; PBX1; ZNF423; FOXG1; SPIB; RBPMS; ZFP36L1; HOXB6; HEY1; BTG1; EMX2; HOXD1; PEG3; TFAP2A; GATA6
Down-regulation	64	ATF1; MYC; CEBPA; KDM5D; SMARCD2; RXRA; RERE; YWHAB; RUNX3; SPI1; TGFB1; SUZ12; PARP1; RBM14; ZBTB7A; PPP1R13L; RNF141; MNT; CBX5; BCL11B; SFPQ; JUP; IRF2; RREB1; ARID1A; SSBP3; NLK; TRAK1; HDAC4; TSC22D2; STAT3; SMAD6; ZMYND8; HMGA2; KAT2B; ZBTB1; NR2F6; HIC2; CNOT6; ZBED1; TRIM22; ZNF544; TXNIP; CHD9; PURA; FOXA1; SSBP2; NR1H3; SNAI2; KLF10; ETV5; LOXL2; SUB1; ELK3; ERG; BASP1; TOB1; MAFB; TOX3; MAF; HOXC10; NRIP1; SUV39H1; E2F2