Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID05994	Alectinib	GSE70138	ASC.C	Human	24h	3.33uM	EID0107

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	TRIM32; CRYM; DAXX; ADRB2; MYT1L; MXD4; ATF3; FOXD1; SMAD2; RARG; ZNF22; MNAT1; KLF5; TBX2; MLLT10; ORC2; HCFC2; ING3; BRD2; MEOX1; TGIF1; SMAD7; NPAT; ZIC1; SIX1; SP3; EPAS1; NKX3-1; ZNF3; BTG1; ELK3; HEY1; SOX9; MECOM; ZFHX4; FOXF1; AHR; ZBED2; ERBB4; SOX11; KLF6; NR1D2; TBX3; NFIB; SSX1; NRBF2; TRIP6; EYA2; ZFP36L1; MEOX2; ZFP36L2; BRD4; BASP1; RBBP8; HOXC6; KDM5D; POU2AF1
Down-regulation	68	HDAC1; NR4A3; TRIM24; TFEC; TCF21; PBX1; GTF3A; PRKDC; MAFF; BCLAF1; FOSL2; MITF; PEG3; ATF4; REL; ZNF331; NR4A2; CAPN15; SFPQ; SREBF1; AEBP1; FOXI1; UBP1; YBX3; PHIP; ZNF394; ZBTB16; BCOR; TSC22D2; FLNA; ZMYND8; SNAI2; ILF2; RREB1; ZNF91; DLX5; PLAGL1; COPS2; ZNF83; TXNIP; DDX17; TGFB1; JUP; ZNF652; HHEX; ZNF266; TOX3; MLXIP; GATA4; RAD21; JAK2; NR4A1; TLE4; ZNF160; MNDA; MEIS2; IRF7; FOXO1; TOB1; LOXL2; ZNF721; ZEB1; EHF; MYBL1; WT1; ZBTB18; E2F2; SUV39H1